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中国西南部云南省傣族人群的HLA等位基因和单倍型分布

HLA alleles and haplotypes distribution in Dai population in Yunnan province, Southwest China.

作者信息

Shi L, Yao Y F, Shi L, Matsushita M, Yu L, Lin Q K, Tao Y F, Oka T, Chu J Y, Tokunaga K

机构信息

Institute of Medical Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Kunming, China.

出版信息

Tissue Antigens. 2010 Feb;75(2):159-65. doi: 10.1111/j.1399-0039.2009.01407.x. Epub 2009 Dec 7.

Abstract

Human leukocyte antigen (HLA) analysis would be a useful tool to trace the origin of modern humans. In this study, we provided the first four digital HLA-A, -B, -C and -DRB1 allele and haplotype data in the Dai ethnic population, which is a unique and representative Kam-Tai-speaking ethnic minority living in the Yunnan province of Southwestern China. Our results showed that the Dai population has unique HLA characteristic that are most closely related to the Southeastern Asia group and similar to the Kam-Tai speaking populations in China and Thailand.

摘要

人类白细胞抗原(HLA)分析将是追溯现代人类起源的有用工具。在本研究中,我们提供了中国西南部云南省一个独特且具代表性的讲侗台语的少数民族——傣族人群中HLA-A、-B、-C和-DRB1等位基因及单倍型的前四组数字数据。我们的结果表明,傣族人群具有独特的HLA特征,这些特征与东南亚群体关系最为密切,且与中国和泰国讲侗台语的人群相似。

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