INSERM, U687, Villejuif F-94807, France.
Drug Alcohol Depend. 2010 Mar 1;107(2-3):257-60. doi: 10.1016/j.drugalcdep.2009.10.016. Epub 2009 Dec 8.
Youths whose parents smoke tobacco may be at elevated risk of smoking themselves. However, the association between parental long-term smoking history and offspring regular tobacco use is not well known. Using data collected on 1121 youths (12-26 years) participating in the GAZEL Youth study, a French community-based cohort, we tested the association between parental long-term smoking trajectory and offspring regular smoking. Parental smoking trajectory over 11 years (1989-1999) was measured by yearly reports obtained from the parent. Statistical analyses controlled for youth's sex, age, alcohol use and disruptive behavioral problems, parent's sex, as well as family socioeconomic position. Overall, 27% of study youths smoked regularly. Compared to offspring of non-smokers, those of persistent smokers had twofold smoking rates (age and sex-adjusted OR: 1.91, 95% CI: 1.30-2.79, fully-adjusted OR: 1.96, 95% CI: 1.31-2.93). Additionally, persistent parental smoking predicted offspring heavy smoking and early smoking initiation. Overall, maternal smoking was more strongly associated with youths' regular smoking than paternal smoking (fully-adjusted ORs: 3.12, 95% 1.58-6.16 vs. 1.47, 95% 0.87-2.49). These results suggest that efforts to decrease the burden of tobacco smoking among youths may be more efficient if focused on families rather than on individuals.
青少年的父母若吸烟，其子女日后吸烟的风险可能会增加。然而，父母长期吸烟史与子女定期吸烟之间的关联尚不清楚。利用参加法国基于社区的 GAZEL 青年研究的 1121 名青少年（12-26 岁）收集的数据，我们检验了父母长期吸烟轨迹与子女定期吸烟之间的关系。11 年内（1989-1999 年）父母的吸烟轨迹通过从父母处获得的年度报告来衡量。统计分析控制了青年的性别、年龄、饮酒和破坏性行为问题、父母的性别以及家庭社会经济地位。总的来说，27%的研究青少年定期吸烟。与非吸烟者的子女相比，持续吸烟者的吸烟率是其两倍（年龄和性别调整后的 OR：1.91，95%CI：1.30-2.79，完全调整后的 OR：1.96，95%CI：1.31-2.93）。此外，持续的父母吸烟预示着子女重度吸烟和早期吸烟开始。总的来说，母亲吸烟与青少年定期吸烟的关联比父亲吸烟更强（完全调整后的 ORs：3.12，95%1.58-6.16 与 1.47，95%0.87-2.49）。这些结果表明，如果将减少青少年吸烟负担的努力集中在家庭而不是个人身上，可能会更有效。
