Diagnostic Radiology Department, Mansoura Faculty of Medicine, Mansoura, Egypt.
Acad Radiol. 2010 Mar;17(3):382-6. doi: 10.1016/j.acra.2009.10.014. Epub 2009 Dec 11.
The aim of this work is to review the techniques and clinical applications of diffusion-weighted magnetic resonance (MR) imaging of the breast. Diffusion-weighted MR imaging plays a role in the differentiation breast cancer from benign lesions, the characterization of malignancy, and the detection of tumor extension. The apparent diffusion coefficient of breast cancer is correlated with tumor cellularity and some prognostic factors of breast cancer. It can be used for the differentiation of recurrent tumors from posttreatment changes and monitoring of patients after chemotherapy. Diffusion-weighted MR imaging is used for the characterization of breast mass, diagnosis, and the grading and staging of breast cancer, as well as prediction of the responses of patients with breast cancer to chemotherapy.
本工作旨在综述磁共振（MR）扩散加权成像技术及其在乳腺疾病中的临床应用。扩散加权 MR 成像在鉴别乳腺良恶性病变、评价病变恶性程度及检测肿瘤侵犯范围方面具有重要作用。乳腺癌的表观扩散系数与肿瘤细胞密度及乳腺癌的某些预后因素相关，有助于鉴别肿瘤复发与治疗后改变，监测乳腺癌患者化疗后的疗效。扩散加权 MR 成像可用于乳腺肿块的定性诊断、乳腺癌分级分期，预测乳腺癌患者对化疗的反应。
