Department of Psychology and the Neuroscience Institute, Princeton University, Princeton, NJ 08540, USA.
Trends Cogn Sci. 2010 Jan;14(1):40-8. doi: 10.1016/j.tics.2009.10.011. Epub 2009 Dec 11.
Response reliability is complementary to more conventional measurements of response amplitudes, and can reveal phenomena that response amplitudes do not. Here we review studies that measured reliability of cortical activity within or between human subjects in response to naturalistic stimulation (e.g. free viewing of movies). Despite the seemingly uncontrolled nature of the task, some of these complex stimuli evoke highly reliable, selective and time-locked activity in many brain areas, including some regions that show little response modulation in most conventional experimental protocols. This activity provides an opportunity to address novel questions concerning natural vision, temporal scale of processing, memory and the neural basis of inter-group differences.
响应可靠性是对响应幅度的更传统测量的补充,并且可以揭示响应幅度无法揭示的现象。在这里,我们回顾了测量人类受试者对自然刺激(例如电影自由观看)的皮质活动可靠性的研究。尽管任务的性质似乎不受控制,但其中一些复杂的刺激会在许多大脑区域中引起高度可靠,选择性和时间锁定的活动,包括在大多数常规实验方案中反应调制很小的一些区域。这种活动为解决有关自然视觉,处理的时间尺度,记忆以及群体间差异的神经基础的新问题提供了机会。