Telethon Institute for Child Health Research, Centre for Child Health Research, The University of Western Australia, Perth, Australia.
J Pediatr. 2010 Apr;156(4):568-74. doi: 10.1016/j.jpeds.2009.10.020. Epub 2009 Dec 14.
To determine whether there was an independent effect of breastfeeding on child and adolescent mental health.
The Western Australian Pregnancy Cohort (Raine) Study recruited 2900 pregnant women and followed the live births for 14 years. Mental health status was assessed by the Child Behaviour Checklist (CBCL) at 2, 6, 8, 10, and 14 years. Maternal pregnancy, postnatal, and infant factors were tested in multivariable random effects models and generalized estimating equations to examine the effects of breastfeeding duration on mental health morbidity.
Breastfeeding for less than 6 months compared with 6 months or longer was an independent predictor of mental health problems through childhood and into adolescence. This relationship was supported by the random effects models (increase in total CBCL score: 1.45; 95% confidence interval 0.59, 2.30) and generalized estimating equation models (odds ratio for CBCL morbidity: 1.33; 95% confidence interval 1.09, 1.62) showing increased behavioral problems with shorter breastfeeding duration.
A shorter duration of breastfeeding may be a predictor of adverse mental health outcomes throughout the developmental trajectory of childhood and early adolescence.
确定母乳喂养对儿童和青少年心理健康是否有独立影响。
西澳大利亚妊娠队列（Raine）研究招募了 2900 名孕妇，并对活产儿进行了 14 年的随访。心理健康状况通过儿童行为检查表（CBCL）在 2、6、8、10 和 14 岁时进行评估。通过多变量随机效应模型和广义估计方程测试了母亲妊娠、产后和婴儿因素，以检查母乳喂养持续时间对心理健康发病率的影响。
与母乳喂养 6 个月或更长时间相比，母乳喂养少于 6 个月是儿童期和青春期心理健康问题的独立预测因素。随机效应模型（CBCL 总分增加：1.45；95%置信区间 0.59，2.30）和广义估计方程模型（CBCL 发病率的优势比：1.33；95%置信区间 1.09，1.62）支持了这一关系，表明母乳喂养时间越短，行为问题越多。
母乳喂养时间较短可能是儿童和青少年整个发育轨迹中不良心理健康结局的预测因素。
