在接受强化免疫抑制治疗的肾移植受者中使用奥司他韦进行甲型H1N1流感暴露后预防。

Postexposure prophylaxis of H1N1 with oseltamivir in a newly transplanted kidney recipient receiving intense immunosuppressive therapy.

作者信息

Marfo K, Chapochnick-Friedmann J, Akalin E, Lu A

机构信息

Department of Pharmacy, Montefiore Medical Center, Bronx, New York, New York 10467, USA.

出版信息

Transplant Proc. 2009 Dec;41(10):4411-3. doi: 10.1016/j.transproceed.2009.09.052.

DOI:10.1016/j.transproceed.2009.09.052

PMID:20005410

Abstract

Solid organ transplant recipients undergoing immunosuppressive therapy are considered to be at high risk for serious infectious complications. Recently in the United States, a pandemic of H1N1 flu infection has been reported with serious complications. We describe H1N1 infection in a living kidney donor and the 42-year-old kidney transplant recipient exposed to this kidney donor and undergoing intense immunosuppressive therapy. Postexposure prophylaxis with oseltamivir was effective to prevent H1N1 influenza A virus in a donor and a recipient.

摘要

接受免疫抑制治疗的实体器官移植受者被认为有发生严重感染并发症的高风险。最近在美国，已报告了甲型H1N1流感感染大流行及严重并发症。我们描述了一名活体肾供者以及一名42岁接受该肾供者肾脏移植并正在接受强化免疫抑制治疗的肾移植受者的甲型H1N1流感感染情况。用奥司他韦进行暴露后预防对供者和受者预防甲型H1N1流感病毒有效。