Ozkan Gulsum, Ulusoy Sukru, Kaynar Kubra, Oztuna Funda, Cansiz Muammer, Kazaz Nazli
Department of Nephrology, Karadeniz Technical University, School of Medicine.
Exp Clin Transplant. 2010 Dec;8(4):318-20.
Influenza pandemics have been observed in several periods throughout history. The first influenza pandemic of the 21st century began in Mexico in 2009 and has spread rapidly all over the world. Swine H1N1 has been officially declared a pandemic by the World Health Organization in June 2009. As has been observed in previous pandemics, pregnant women, adolescents, and immunosuppressed individuals are affected more severely in this pandemic. Despite several reports about the pandemic, there have not been any reports of swine H1N1 infection in individuals who underwent renal transplant. The aim of the current study was to present oseltamivir therapy in a swine H1N1-infected patient who underwent renal transplant 10 months earlier, and was thus under immunosuppressive treatment. To the best of our knowledge, this is the first case report of a swine H1N1 infection in a renal transplant recipient.
历史上曾在多个时期观察到流感大流行。21世纪的首次流感大流行于2009年在墨西哥爆发,并迅速蔓延至全球。2009年6月,世界卫生组织正式宣布甲型H1N1流感为大流行疾病。正如在以往的大流行中所观察到的那样,孕妇、青少年和免疫功能低下的个体在此次大流行中受到的影响更为严重。尽管有几篇关于此次大流行的报道,但尚未有关于肾移植受者感染甲型H1N1流感的报告。本研究的目的是介绍一名10个月前接受肾移植并因此接受免疫抑制治疗的甲型H1N1流感感染患者的奥司他韦治疗情况。据我们所知,这是肾移植受者感染甲型H1N1流感的首例病例报告。