Department of Medicine and Epidemiology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
Adv Chronic Kidney Dis. 2010 Jan;17(1):5-18. doi: 10.1053/j.ackd.2009.08.003.
Despite recent improvements in the efficacy, safety, tolerability, and convenience of antiretroviral therapy for patients, the management of HIV infection remains complex for clinicians. Multiple studies have shown better clinical outcomes and lower cost of care when HIV-infected patients are managed by experts. However, generalists are frequently involved in the care of patients with HIV infection, in many cases providing primary care in collaboration with an HIV expert. Generalists also play a critical role in the diagnosis and prevention of HIV infection. Generalists managing HIV-infected patients should be aware of the components of the initial patient evaluation. They should be familiar with the general principles of antiretroviral therapy and opportunistic infection prevention. They should be able to recognize antiretroviral toxicity and should be aware of common drug-drug interactions involving antiretroviral agents.
尽管抗逆转录病毒疗法在患者的疗效、安全性、耐受性和便利性方面最近有所改善，但对于临床医生来说，艾滋病毒感染的管理仍然很复杂。多项研究表明，当感染艾滋病毒的患者由专家管理时，会有更好的临床结果和更低的护理成本。然而，在许多情况下，全科医生经常参与艾滋病毒感染者的护理工作，与艾滋病毒专家合作提供初级保健。全科医生在艾滋病毒感染的诊断和预防中也起着至关重要的作用。管理艾滋病毒感染者的全科医生应该了解初始患者评估的组成部分。他们应该熟悉抗逆转录病毒治疗和机会性感染预防的一般原则。他们应该能够识别抗逆转录病毒毒性，并且应该了解涉及抗逆转录病毒药物的常见药物相互作用。
