AbuRahma A F, Robinson P A, Boland J P, Lucente F C, Stuart S P, Neuman S S, Hall M D, Hoak B A
Department of Surgery, West Virginia University Health Sciences Center/Charleston Area Medical Center.
Surgery. 1991 Mar;109(3 Pt 1):244-51.
This study analyzed 33 variables that might potentially affect outcome in a series of 332 consecutive elective abdominal aortic aneurysm repairs in a southern West Virginia community. One of the interesting features of this series was that the repairs were done by 22 surgeons with varying degrees of experience. The mortality and complication rates were compared for various potential risk factors by both univariant methods (chi 2, Fisher's exact, and Student t tests) and multivariant methods of analysis. Our early mortality (2.1%) and postoperative complication rates were consistent with those of other series. With multiple linear regression models, five factors were selected as significant independent risk factors associated with an increasing number of postoperative complications: the number of blood transfusions (p less than 0.0001), left renal vein ligation (p less than 0.0001), the presence of greater than 50% renal artery stenosis (p = 0.0012), the lesser experience of the surgeon (p = 0.0203), and the history of prior cardiac catheterization (p = 0.0245). The only factor statistically correlated with mortality rate was an increased number of postoperative complications (p less than 0.0001). Neither postoperative complications nor mortality rate was found to be significant and independently influenced by other demographic, clinical, or operative factors. It is tempting to speculate that surgeons with less experience might be well served to refer patients with significant renal artery stenosis and coronary artery disease. Our mortality and complication rates were not increased by performing preoperative angiography and therefore prudent surgeons may find this helpful in selecting patients for safer repair.
本研究分析了一系列332例在西弗吉尼亚州南部社区连续进行的择期腹主动脉瘤修复手术中可能影响手术结果的33个变量。该系列手术的一个有趣特点是,手术由22位经验程度不同的外科医生完成。通过单变量方法(卡方检验、Fisher精确检验和学生t检验)和多变量分析方法,对各种潜在风险因素的死亡率和并发症发生率进行了比较。我们的早期死亡率(2.1%)和术后并发症发生率与其他系列报道一致。通过多元线性回归模型,确定了五个因素为与术后并发症数量增加相关的显著独立风险因素:输血次数(p<0.0001)、左肾静脉结扎(p<0.0001)、肾动脉狭窄超过50%(p = 0.0012)、外科医生经验较少(p = 0.0203)以及既往心脏导管插入术史(p = 0.0245)。与死亡率在统计学上相关的唯一因素是术后并发症数量增加(p<0.0001)。未发现术后并发症和死亡率受其他人口统计学、临床或手术因素的显著独立影响。可以推测,经验较少的外科医生最好将有明显肾动脉狭窄和冠状动脉疾病的患者转诊。我们的死亡率和并发症发生率并未因术前血管造影而增加,因此谨慎的外科医生可能会发现这有助于选择患者进行更安全的修复手术。