Endocrinology Unit, Hospital Sant Joan de Déu, University of Barcelona, Barcelona, Spain.
J Pediatr. 2010 Jan;156(1):145-7. doi: 10.1016/j.jpeds.2009.06.050.
Breast-fed infants born small-for-gestational-age (SGA) (n = 28) were found to develop lower adiposity across early infancy, when compared with appropriate-for-gestational age infants (n = 46). The SGA infants were also found to have 2-fold higher (P < .001) levels of circulating leptin at 4 months. This paradoxical hyperleptinemia in early infancy may contribute to a program that produces a process from fetal underweight to adult overweight.
与适于胎龄的婴儿（n = 46）相比，出生时为小于胎龄儿（SGA）的母乳喂养婴儿（n = 28）在婴儿早期的体脂发育较低。还发现 SGA 婴儿在 4 个月时的循环瘦素水平高出 2 倍（P <.001）。这种在婴儿早期的反常性高瘦素血症可能促成了一个从胎儿体重不足到成年超重的过程。
