Biomedical Laboratory Diagnostics Program, Michigan State University, 322 North Kedzie Hall, East Lansing, MI 48824-1031, USA.
J Clin Microbiol. 2010 Feb;48(2):427-32. doi: 10.1128/JCM.01589-09. Epub 2009 Dec 9.
Conidiobolus lamprauges, a soil and plant entomophthoralean fungus, has been reported only in a horse and, more recently, in sheep with rhinopharyngeal entomophthoramycosis. Thus, little information is available to enable proper identification of this pathogen and its differentiation from other saprotrophic and pathogenic Conidiobolus species. Using classical mycological tools and molecular methodologies, we report for the first time the taxonomic and phylogenetic description of three C. lamprauges isolates recovered from sheep with rhinopharyngeal entomophthoramycosis. The distinctive clinical and pathological features of C. lamprauges are compared with those of other Conidiobolus spp. affecting sheep, as well as with those of the stramenopilan ovine agent Pythium insidiosum. The comparative morphological attributes of Conidiobolus spp. are also diagramed; along with the sequence data generated, they should assist laboratories in the identification of these uncommon species.
亮卡盾皮菌是一种土壤和植物中的内腐真菌，仅在马中以及最近在患有鼻咽喉部昆虫真菌病的绵羊中被报道过。因此，对于这种病原体，我们几乎没有足够的信息来进行正确的鉴定并将其与其他腐生和致病性的盾皮菌物种区分开来。利用经典的真菌学工具和分子方法学，我们首次报告了从患有鼻咽喉部昆虫真菌病的绵羊中分离出的三个亮卡盾皮菌分离株的分类和系统发育描述。将亮卡盾皮菌的独特临床和病理特征与其他影响绵羊的盾皮菌物种以及绵羊的藻菌纲病原体绵霉病菌进行了比较。还绘制了盾皮菌属的比较形态学特征图；结合生成的序列数据，这些信息应该有助于实验室鉴定这些不常见的物种。
