Department of Neurology, Aarhus University Hospital in Aalborg, Denmark.
Mult Scler. 2010 Jan;16(1):121-6. doi: 10.1177/1352458509352196. Epub 2009 Dec 9.
Multiple sclerosis affects young and middle-aged people and often leads to physical and cognitive handicaps. There is a need for detailed knowledge of the social consequences of the disease. We aim here to describe the course of the working life and career of multiple sclerosis patients at the time of onset and thereafter, in terms of probability of early pension and income development. All 2538 patients with multiple sclerosis in Denmark with disease onset between 1980 and 1989, identified through the Danish MS-Registry, were included in this study. Twenty matched control persons per patient were randomly drawn from the civil registration system. Information on economic status was retrieved from Statistics Denmark. A survival analysis technique was used with onset as the starting point. We found that the probability of remaining without early pension was at 5 years 70% for patients and 97% for controls, and at 20 years 22% for patients and 86% for controls. Due to lower rates for early pension, gross income with time was lower in patients than controls. We conclude that multiple sclerosis seriously affects the economic life of multiple sclerosis patients, even within a few years of onset.
多发性硬化症影响年轻人和中年人，常常导致身体和认知障碍。需要详细了解疾病的社会后果。我们旨在描述多发性硬化症患者在发病时及之后的工作生涯和职业发展情况，包括提前退休的可能性和收入的发展情况。所有 2538 名在丹麦 1980 年至 1989 年间发病的多发性硬化症患者，都是通过丹麦多发性硬化症登记处确定的，都纳入了这项研究。每个患者随机抽取 20 名匹配的对照者，对照者来自民事登记系统。丹麦统计局检索了有关经济状况的信息。采用生存分析技术，以发病为起点。我们发现，在发病后 5 年内，患者没有提前退休的可能性为 70%，而对照组为 97%；在 20 年内，患者为 22%，而对照组为 86%。由于提前退休的比例较低，患者的总收入随着时间的推移低于对照组。我们的结论是，多发性硬化症严重影响多发性硬化症患者的经济生活，甚至在发病后的几年内也是如此。
