Department of Plant Pathology and Microbiology, University of California, Riverside, California 92521, USA.
Appl Environ Microbiol. 2010 Feb;76(3):936-41. doi: 10.1128/AEM.01561-09. Epub 2009 Dec 11.
This study examined bacteria-immune interactions in a mouse model possessing microbiota-dependent immune regulatory features similar to those occurring in human atopy, colitis, and immune regulation. Associations between the abundance of several bacterial phylotypes and immunoregulatory target cell types were identified, suggesting that they may play a role in these phenotypes.
本研究在一种具有与人类特应性、结肠炎和免疫调节中相似的微生物群依赖性免疫调节特征的小鼠模型中研究了细菌-免疫相互作用。鉴定了几种细菌类群与免疫调节靶细胞类型之间的丰度相关性,表明它们可能在这些表型中发挥作用。