Institute for Hygiene and Pathology of Animal Nutrition, Veterinary Faculty, University of Ljubljana, Gerbiceva 60, 1000 Ljubljana, Slovenia.
Vet Rec. 2009 Dec 12;165(24):713-8.
Two groups of 10 pregnant gilts (89 +/- 2 days gestation) were fed either an experimental diet that contained 5.08 mg/kg deoxynivalenol, 0.09 mg/kg zearalenone and 21.6 mg/kg fusaric acid, or a control diet that contained 0.29 mg/kg deoxynivalenol, <0.02 mg/kg zearalenone and <0.77 mg/kg fusaric acid. The concentrations of immunoglobulins were measured in sera of the gilts and in the colostrum and serum of the piglets by radial immunodiffusion. The feed consumption of the sows fed the experimental diet was significantly lower and the overall growth rate of their piglets was significantly reduced. On average, parturition took 80 minutes longer in sows fed the experimental diet. On day 17 after parturition, the concentration of IgM in the serum of the experimental gilts was significantly higher, but the concentration of IgA in their colostrum was significantly lower, than in the control gilts. In the serum of the piglets 12, 24 and 48 hours after first suckling, the concentrations of IgA and IgG were significantly lower in those farrowed by the sows fed the experimental diet than in those farrowed by the sows fed the control diet.
两组各 10 头怀孕母猪（89 +/- 2 天妊娠）分别饲喂含有 5.08 毫克/千克脱氧雪腐镰刀菌烯醇、0.09 毫克/千克玉米赤霉烯酮和 21.6 毫克/千克伏马菌素的试验饲料或含有 0.29 毫克/千克脱氧雪腐镰刀菌烯醇、<0.02 毫克/千克玉米赤霉烯酮和 <0.77 毫克/千克伏马菌素的对照饲料。通过放射免疫扩散法测量了母猪血清和仔猪初乳及血清中的免疫球蛋白浓度。饲喂试验饲料的母猪采食量显著降低，其仔猪的总生长率显著降低。平均而言，饲喂试验饲料的母猪分娩时间延长了 80 分钟。分娩后第 17 天，试验组母猪血清中 IgM 浓度显著升高，但初乳中 IgA 浓度显著降低。在首次哺乳后 12、24 和 48 小时，饲喂试验饲料母猪所产仔猪的血清中 IgA 和 IgG 浓度明显低于饲喂对照饲料母猪所产仔猪。
