Centre for Contact Lens Research, University of Waterloo, Waterloo, ON, Canada.
Eye Contact Lens. 2010 Jan;36(1):10-8. doi: 10.1097/ICL.0b013e3181c5b385.
The purpose of this study was to measure the advancing and receding contact angles (CAs) of five daily disposable (DD) lenses and the osmolality, surface tension (ST), and pH of each blister pack solution.
The advancing and receding CAs were measured directly out of the blister pack for five DD lenses: omafilcon A (CooperVision), nelfilcon A (CIBA Vision), modified nelfilcon A (CIBA Vision), etafilcon A (Johnson & Johnson), and narafilcon A (Johnson & Johnson). Advancing CAs were measured using sessile drop and Wilhelmy balance methods. Receding CAs were measured using the Wilhelmy balance method. ST, pH, and osmolality were measured for each blister pack solution from all the DD lenses.
The advancing CAs for the nelfilcon A lenses were statistically lower (P<0.05) than the advancing CAs of the other three lenses. The receding CAs for etafilcon A were statistically lower (P<0.05) than the receding CAs for the other four lenses. The pH of all the blister pack solutions was relatively neutral (7.01-7.43). The ST of the blister pack solution for the modified nelfilcon A was significantly lower (P<0.05) than the ST of all other blister pack solutions. The osmolality of the blister pack solutions for the etafilcon A and narafilcon A lenses were significantly higher (P<0.05) than the other blister pack solutions.
The modified nelfilcon A lens had low advancing CAs and low receding CAs showing minimal hysteresis. The blister pack solution for the modified nelfilcon A lens had the lowest ST, a low osmolality, and a neutral pH.
本研究旨在测量五款日抛型（DD）隐形眼镜的前进接触角（CA）和后退接触角（CA），以及每个泡罩包装溶液的渗透压、表面张力（ST）和 pH 值。
直接从泡罩包装中测量五款 DD 隐形眼镜（库博视康的欧舒适、CIBA Vision 的新舒适、改良型新舒适、强生日晰的纯视 2 和强生的纳美）的前进 CA 和后退 CA。前进 CA 采用悬滴法和吊片法测量，后退 CA 采用吊片法测量。测量每个泡罩包装溶液的 ST、pH 值和渗透压。
新舒适镜片的前进 CA 明显低于其他三种镜片（P<0.05）。与其他四种镜片相比，纯视 2 的后退 CA 明显更低（P<0.05）。所有泡罩包装溶液的 pH 值均相对中性（7.01-7.43）。改良型新舒适泡罩包装溶液的 ST 明显低于其他所有泡罩包装溶液（P<0.05）。纯视 2 和纳美泡罩包装溶液的渗透压明显高于其他泡罩包装溶液（P<0.05）。
改良型新舒适镜片具有低前进 CA 和低后退 CA，表现出最小的滞后现象。改良型新舒适镜片的泡罩包装溶液具有最低的 ST、低渗透压和中性 pH 值。
