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慢性精神分裂症和痴呆症患者的临终清醒:文献综述

Terminal lucidity in patients with chronic schizophrenia and dementia: a survey of the literature.

作者信息

Nahm Michael, Greyson Bruce

出版信息

J Nerv Ment Dis. 2009 Dec;197(12):942-4. doi: 10.1097/NMD.0b013e3181c22583.

DOI:10.1097/NMD.0b013e3181c22583
PMID:20010032
Abstract

In this article, we present the results of a literature survey on case reports of the unexpected return of mental clarity and memory shortly before death, which we have called "terminal lucidity." We focus specifically on terminal lucidity in mental disorders, of which we have found 81 case references. Of these, we were able to retrieve 49 case reports, most of which had been recorded before 1849. Thereafter, comparatively few reports of terminal lucidity have been published. Some more recent publications referred to terminal lucidity in patients suffering from schizophrenia and dementia. We draw parallels and distinctions between terminal lucidity and remissions attributable to febrile illness in neurosyphilis. We recommend in-depth studies on the psychopathology and neuropathology involved in terminal lucidity, since they might enable the development of both improved therapies and a better understanding of unresolved aspects of cognition and memory processing.

摘要

在本文中,我们展示了一项文献调查的结果,该调查涉及死亡前不久精神清晰度和记忆力意外恢复的病例报告,我们将其称为“临终清醒”。我们特别关注精神障碍中的临终清醒,为此我们找到了81个病例参考文献。其中,我们能够检索到49份病例报告,其中大部分是1849年以前记录的。此后,关于临终清醒的报告发表得相对较少。一些较新的出版物提到了精神分裂症和痴呆症患者的临终清醒。我们对临终清醒与神经梅毒发热性疾病所致缓解进行了比较和区分。我们建议对临终清醒所涉及的精神病理学和神经病理学进行深入研究,因为这可能有助于开发更好的治疗方法,并更好地理解认知和记忆处理中尚未解决的方面。

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