Hankinson J L, Bang K M
Division of Respiratory Disease Studies, National Institute for Occupational Safety and Health, Morgantown, West Virginia 26505.
Am Rev Respir Dis. 1991 Mar;143(3):516-21. doi: 10.1164/ajrccm/143.3.516.
An analysis of spirograms of 6,486 subjects from the general population, ages 8 to 90, was conducted to determine their ability to satisfy the American Thoracic Society's (ATS) acceptability and reproducibility criteria. The results indicate that both older and younger subjects had more difficulty satisfying the ATS acceptability and reproducibility criteria. The difficulty in satisfying the ATS reproducibility criterion, particularly in younger subjects, was in part associated with their smaller heights and lung volumes. A relatively uniform within-subject variability of FVC and FEV1 in terms of the mean differences between the largest and second largest FVC and FEV1, for all heights, was observed. In addition, unlike the ATS reproducibility criterion, when a constant 200-ml reproducibility criterion for FVC and FEV1 was used, there was no longer a significant difference between the number of reproducibility criterion failures for the 14 different height groups used. These results suggest that the ATS reproducibility criterion, based on a percentage of the FVC and FEV1, may inappropriately classify a higher percentage of subjects with smaller heights and lung volumes as having a nonreproducible test. In contrast, subjects with larger heights and lung volumes are much less likely to fail the ATS reproducibility requirement. These results emphasize the importance of following the ATS recommendation of using the reproducibility criterion only as a goal during data collection, not to classify a subject as having an invalid test.
对来自普通人群、年龄在8至90岁之间的6486名受试者的肺量图进行了分析，以确定他们满足美国胸科学会（ATS）可接受性和重复性标准的能力。结果表明，老年和年轻受试者在满足ATS可接受性和重复性标准方面都存在更多困难。满足ATS重复性标准的困难，尤其是在年轻受试者中，部分与他们较矮的身高和较小的肺容积有关。观察到在所有身高范围内，FVC和FEV1在最大和第二大FVC及FEV1之间的平均差异方面，受试者内部具有相对一致的变异性。此外，与ATS重复性标准不同，当使用恒定的200毫升FVC和FEV1重复性标准时，所使用的14个不同身高组在重复性标准失败数量上不再存在显著差异。这些结果表明，基于FVC和FEV1百分比的ATS重复性标准可能会不适当地将更高比例的身高和肺容积较小的受试者归类为测试结果不可重复。相比之下，身高和肺容积较大的受试者更不容易不满足ATS重复性要求。这些结果强调了遵循ATS建议的重要性，即在数据收集期间仅将重复性标准作为一个目标，而不是将受试者归类为测试无效。
