化脓性汗腺炎的患病率及相关因素：两项病例对照研究的结果

Prevalence and factors associated with hidradenitis suppurativa: results from two case-control studies.

作者信息

Revuz Jean E, Canoui-Poitrine Florence, Wolkenstein Pierre, Viallette Cedric, Gabison Germaine, Pouget Florence, Poli Florence, Faye Ousmane, Roujeau Jean Claude, Bonnelye Genevieve, Grob Jean Jacques, Bastuji-Garin Sylvie

机构信息

AP-HP, Groupe Henri-Mondor Albert-Chenevier, Service de Dermatologie, Creteil, France, Universite Paris 12, Faculte de Medecine, Creteil, France.

出版信息

J Am Acad Dermatol. 2008 Oct;59(4):596-601. doi: 10.1016/j.jaad.2008.06.020.

DOI:10.1016/j.jaad.2008.06.020

PMID:18674845

Abstract

BACKGROUND

Conflicting opinions have been reported regarding the epidemiology of hidradenitis suppurativa.

OBJECTIVE

We sought to evaluate the prevalence of hidradenitis suppurativa and to identify associated factors.

METHODOLOGY

Prevalence was evaluated using a representative sample of the French population (n=10,000). Associated risk factors were assessed using two case-control studies, one population-based with 67 self-reported patients and 200 control subjects, and the other clinic-based with 302 medically assessed patients and 906 control subjects.

RESULTS

The prevalence was 1% of the French population. Multivariate analyses showed a strong association with current smoking in self-reported (odds ratio=4.16, 95% confidence interval [2.99-8.69]) and in medically assessed (odds ratio=12.55 [8.58-18.38]) populations. Association with body mass index was significant in medically assessed patients (odds ratio=1.12 [1.08-1.15]) for each increase of 1 U of BMI.

LIMITATIONS

A causal relationship could not be established with such a cross-sectional study.

CONCLUSION

Hidradenitis suppurativa is a common disease, frequently associated with smoking and being overweight.

摘要

背景

关于化脓性汗腺炎的流行病学，已有相互矛盾的观点报道。

目的

我们旨在评估化脓性汗腺炎的患病率并确定相关因素。

方法

使用法国人群的代表性样本（n = 10,000）评估患病率。使用两项病例对照研究评估相关危险因素，一项基于人群，有67名自我报告的患者和200名对照受试者，另一项基于诊所，有302名经医学评估的患者和906名对照受试者。

结果

患病率为法国人群的1%。多变量分析显示，在自我报告人群（比值比 = 4.16，95%置信区间[2.99 - 8.69]）和经医学评估的人群（比值比 = 12.55 [8.58 - 18.38]）中，与当前吸烟有很强的关联。在经医学评估的患者中，体重指数每增加1个单位，关联就很显著（比值比 = 1.12 [1.08 - 1.15]）。