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以类固醇反应性左心室心脏肿块为表现的变应性肉芽肿性血管炎。

Churg-Strauss vasculitis presenting with steroid-responsive left ventricular cardiac mass.

作者信息

Alarfaj Sumaiah Jamal, Al-Mehisen Rabah, Elhag Imad, Kazzaz Nayef Mohammed

机构信息

Department of Pharmacy Practice, College of Pharmacy, Princess Nourah bint Abdulrahman University, Riyadh, Saudi Arabia.

Division of Cardiology, Department of Internal Medicine, Security Forces Hospital Program, Riyadh, Saudi Arabia.

出版信息

BMJ Case Rep. 2018 Oct 17;2018:bcr-2018-226052. doi: 10.1136/bcr-2018-226052.

DOI:10.1136/bcr-2018-226052
PMID:30337285
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6254378/
Abstract

A 35-year-old black Saudi man, with a known case of bronchial asthma and allergic rhinitis since childhood, presented with joint pain and swelling, orthopnoea, paroxysmal nocturnal dyspnoea and lower extremity oedema. On examination, we found jugular venous distension, bilateral basal crepitation, wheezing and diffuse synovitis. Investigations were notable for peripheral blood eosinophilia, pericardial effusion and elongated structure in the left ventricular outflow tract on echocardiography, mediastinal and hilar lymphadenopathy and right upper lobe infiltrate on high-resolution CT scan. Pulmonary infiltrate biopsy confirmed eosinophilic vasculitis. Intracardiac mass resolved shortly after pulse steroids indicating an inflammatory mass.

摘要

一名35岁的沙特黑人男性,自幼患有支气管哮喘和过敏性鼻炎,现出现关节疼痛、肿胀、端坐呼吸、阵发性夜间呼吸困难和下肢水肿。检查时,我们发现颈静脉怒张、双侧肺底湿啰音、哮鸣音和弥漫性滑膜炎。检查结果显示外周血嗜酸性粒细胞增多、心包积液、超声心动图显示左心室流出道有细长结构、纵隔和肺门淋巴结肿大以及高分辨率CT扫描显示右上叶浸润。肺浸润活检证实为嗜酸性血管炎。心脏肿块在使用脉冲类固醇后不久消失,提示为炎性肿块。

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Cardiac involvement in granulomatosis with polyangiitis: a magnetic resonance imaging study of 31 consecutive patients.肉芽肿性多血管炎的心脏受累:对31例连续患者的磁共振成像研究
Rheumatology (Oxford). 2017 Jun 1;56(6):947-956. doi: 10.1093/rheumatology/kew490.
2
ANCA-negative eosinophilic granulomatosis with polyangitis (EGPA) manifesting as a large intracardiac thrombus and glomerulonephritis with angionecrosis.抗中性粒细胞胞浆抗体阴性的嗜酸性肉芽肿性多血管炎(EGPA)表现为巨大心内血栓和伴有血管坏死的肾小球肾炎。
BMJ Case Rep. 2016 Sep 2;2016:bcr2016216520. doi: 10.1136/bcr-2016-216520.
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Prevalence and prognostic relevance of cardiac involvement in ANCA-associated vasculitis: eosinophilic granulomatosis with polyangiitis and granulomatosis with polyangiitis.抗中性粒细胞胞浆抗体相关性血管炎中心脏受累的患病率及预后相关性:嗜酸性肉芽肿性多血管炎和肉芽肿性多血管炎
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