CESAM and Departamento de Biologia - Universidade de Aveiro, Portugal.
Chemosphere. 2010 Feb;78(7):907-13. doi: 10.1016/j.chemosphere.2009.10.063. Epub 2009 Dec 16.
Endocrine Disruptor Compounds (EDCs) have been largely studied concerning their effects on vertebrates. Nevertheless, invertebrates as targets for these chemicals have been neglected and few studies are available. Specifically for edaphic invertebrates, data concerning the effects of EDCs is residual. Influences of EDCs on the reproduction systems of these organisms, with consequences at the population level, are expected but have not been confirmed. This work aimed to study the effects of bisphenol A (BPA) and vinclozolin (Vz) on the reproduction of the terrestrial isopod Porcellio scaber. Isopods were coupled and exposed to increasing concentrations of Vz and BPA and the females' reproductive cycle followed for 56d. Both compounds elicited reproductive toxicity. Vz and BPA decreased female reproductive allocation. Vz reduced pregnancy duration; increased the abortion percentage; decreased the number of pregnancies; and decreased the number of juveniles per female while BPA increased abortions at the lowest and highest test concentrations. The reproductive endpoints presented in here are indicative of the possible impact that this type of compounds might have on isopod population dynamics, which may eventually lead to population decline.
内分泌干扰化合物 (EDCs) 已在很大程度上因其对脊椎动物的影响而受到研究。然而，这些化学物质对无脊椎动物的影响却被忽视了，可用的研究很少。特别是对于土壤无脊椎动物，有关 EDC 影响的数据仍然很少。预计 EDCs 会对这些生物体的生殖系统产生影响，进而对种群水平产生影响，但尚未得到证实。本研究旨在研究双酚 A (BPA) 和 vinclozolin (Vz) 对陆生等足目 Porcellio scaber 生殖的影响。将等足目动物配对并暴露于递增浓度的 Vz 和 BPA 下，然后对雌性的生殖周期进行了 56 天的跟踪观察。这两种化合物都表现出生殖毒性。Vz 和 BPA 降低了雌性的生殖分配。Vz 缩短了妊娠持续时间；增加了流产率；减少了怀孕次数；并且减少了每只雌性的幼体数量，而 BPA 则在最低和最高测试浓度下增加了流产次数。这里呈现的生殖终点表明，这类化合物可能对等足目种群动态产生潜在影响，最终可能导致种群数量下降。
