Department of Internal Medicine, Division of Immunobiology, Section of Allergy & Clinical Immunology, Saint Louis University School of Medicine, 1402 South Grand Boulevard, M157, Saint Louis, MO 63104, USA.
Allergy Asthma Clin Immunol. 2009 Dec 1;5(1):9. doi: 10.1186/1710-1492-5-9.
Rhinitis in the elderly is a common but often neglected condition. Structural changes in the nose associated with aging, predisposes the elderly to rhinitis. There are a number of specific factors that affect medical treatment of the elderly including polypharmacy, cognitive dysfunction, changes in body composition, impairment of liver and renal function and the cost of medications in the face of limited resources. Rhinitis in the elderly can be placed in several categories and treatment should be appropriate for each condition. The most important aim is to moisten the nasal mucosa since the nose of the elderly is so dry. Great caution should be used in treatment with first generation antihistamines and decongestants. Medications generally well tolerated by the elderly are second generation antihistamines, intra-nasal anti-inflammatory agents, leukotriene modifiers and iprapropium nasal spray.
老年人鼻炎是一种常见但常被忽视的疾病。与衰老相关的鼻腔结构变化使老年人易患鼻炎。有许多特定的因素会影响老年人的医疗治疗,包括多药治疗、认知功能障碍、身体成分的变化、肝肾功能的损害以及在资源有限的情况下药物的成本。老年人的鼻炎可以分为几类,治疗应针对每种情况。最重要的目标是滋润鼻腔黏膜,因为老年人的鼻腔非常干燥。在使用第一代抗组胺药和减充血剂治疗时应格外小心。一般来说,第二代抗组胺药、鼻内抗炎药、白三烯调节剂和异丙托溴铵鼻喷剂是老年人能很好耐受的药物。