Tarayre J P, Delhon A, Lauressergues H
Arch Int Pharmacodyn Ther. 1977 Jul;228(1):162-70.
In the rat, the injection of Bordetella pertussis produces, after prior sensitization, a delayed hypersensitivity inflammatory reaction within the pleural cavity. The influence of various methods of sensitization on this hypersensitivity was studied in the Sprague Dawley rat. The reaction was very variable according to the experimental conditions used. Optimal sensitization was obtained following the injection of antigen mixed with complete Freund's adjuvant into the dorsal surface of the paws.
在大鼠中，预先致敏后注射百日咳博德特氏菌会在胸腔内引发迟发型超敏反应性炎症。在斯普拉格-道利大鼠中研究了各种致敏方法对这种超敏反应的影响。根据所采用的实验条件，反应差异很大。将抗原与完全弗氏佐剂混合后注射到爪的背表面可获得最佳致敏效果。
