[2008年北京奥运会期间老年易感人群空气质量与心率变异性的相关性]

[The correlations between air quality and heart rate variability in aged susceptible people during Beijing Olympic Games 2008].

作者信息

Jia Yu-ping, Guo Yu-ming, Wang Zhen-yu, Xie Yong-zhen, Tang Xiao-yan, Zhu Tong, Wang Sheng, Pan Xiao-chuan

机构信息

Department of Occupational and Environmental Health, Peking University School of Public Health, Beijing 100191, China.

出版信息

Zhonghua Yu Fang Yi Xue Za Zhi. 2009 Aug;43(8):669-73.

PMID:20021844

Abstract

OBJECTIVE

To observe the variations of the concentrations of air pollutants and explore the correlation between the heart rate variability (HRV) of the aged people and the air quality during Beijing Olympic Games 2008.

METHODS

A panel study design was adopted. A total of twenty-six over 55-year-old patients with coronary heart disease or angina pectoris or a symptom of myocardial ischemia at least for one year were enrolled as a panel and followed up five times by measuring HRV index and other related indexes from June to September in 2008. The correlations between the HRV of the aged people and the air quality was analyzed with the linear mixed-effect models according to the data of air pollutants and meteorological conditions collected simultaneously from Beijing Environmental Protection Bureau and Beijing Meteorological Bureau.

RESULTS

In single-pollutant mixed-effect models, the significant correlation was observed in the reduction of ambient PM(10), SO(2) and NO(2) with the improvement of the total power and high-frequency power (HF) of HRV in the panel subjects, and a 10 microg/m(3) decrease in PM(10), SO(2) and NO(2) level was correlated with 2.51% (95%CI: -3.80% - -1.22%, t = -1.99, P = 0.0497), 31.39% (95%CI: -52.24% - -10.53%, t = -1.99, P = 0.0497) and 42.72% (95%CI: -75.06% - -10.38%, t = -1.99, P = 0.0497) rises in total power of HRV respectively. A 10 microg/m(3) decrease in PM(10), SO(2) and NO(2) level was correlated with 3.46% (95%CI: -5.14% - -1.77%, t = -2.11, P = 0.0378), 40.63% (95%CI: -68.70% - -12.56%, t = -2.11, P = 0.0378) and 53.76% (95%CI: -97.97% - -9.56%, t = -2.11, P = 0.0378) rises in high-frequency power (HF) of HRV respectively.

CONCLUSION

It suggests that the air pollution reduction could improve the cardiovascular functions of the susceptible population.

摘要

目的

观察2008年北京奥运会期间空气污染物浓度变化，探讨老年人心率变异性（HRV）与空气质量的相关性。

方法

采用队列研究设计。选取26例年龄在55岁以上，患有冠心病、心绞痛或至少有一年心肌缺血症状的患者作为队列，于2008年6月至9月对其进行5次随访，测量HRV指标及其他相关指标。根据同时从北京市环境保护局和北京市气象局收集的空气污染物和气象条件数据，采用线性混合效应模型分析老年人HRV与空气质量的相关性。

结果

在单污染物混合效应模型中，观察到环境中PM(10)、SO(2)和NO(2)浓度降低与队列研究对象HRV的总功率和高频功率（HF）改善之间存在显著相关性，PM(10)、SO(2)和NO(2)水平每降低10μg/m(3)，HRV总功率分别升高2.51%（95%CI：-3.80%--1.22%，t = -1.99，P = 0.0497）、31.39%（95%CI：-52.24%--10.53%，t = -1.99，P = 0.0497）和42.72%（95%CI：-75.06%--10.38%，t = -1.99，P = 0.0497）。PM(10)、SO(2)和NO(2)水平每降低10μg/m(3)，HRV高频功率（HF）分别升高3.46%（95%CI：-5.14%--1.77%，t = -2.11，P = 0.0378）、40.63%（95%CI：-68.70%--12.56%，t = -2.11，P = 0.0378）和53.76%（95%CI：-97.97%--9.56%，t = -2.11，P = 0.0378）。