Department of Endodontics, Faculty of Odontology, Malmö University, Carl Gustafs väg 34, SE-20506 Malmö, Sweden Department of Clinical Oral Physiology, School of Dentistry, Aarhus University, Aarhus, Denmark Department of Oral Maxillofacial Surgery, Aarhus University Hospital, Aarhus, Denmark Departments of Oral Medicine and Dental Public Health Sciences, University of Washington, Seattle, WA, USA Orofacial Pain Unit, Department of Stomatognathic Physiology, Faculty of Odontology, Malmö University, Malmö, Sweden.
Pain. 2010 Feb;148(2):220-226. doi: 10.1016/j.pain.2009.10.024. Epub 2009 Dec 21.
The German Research Network on Neuropathic Pain (DFNS) has recommended a protocol with 13 quantitative sensory testing (QST) measures for detecting somatosensory abnormalities. Reliability is an important scientific property and has been adequately tested for cutaneous QST. This study evaluates intraoral sites for which no reliability trials have yet been published. Inter- and intra-examiner reliability of 13 QST measures at intra- and extraoral trigeminal sites were investigated. Twenty-one healthy volunteers from Malmö University, Malmö, Sweden (13 women and 8 men, mean age 40.4 years, range 24-71) participated. Two independent examiners previously trained in the DFNS QST protocol examined the participants using the entire protocol. Each participant was examined twice on the same day, once by each examiner (inter-examiner reliability). After 1-3 weeks, one examiner re-examined all participants (intra-examiner reliability). The measurements were made on the skin of the right cheek, the tip of the tongue, and bilaterally on the gingival mucosa of the upper premolar region. The intraclass correlation coefficient (ICC) or kappa was used to calculate variations. Most tests had acceptable to excellent inter-examiner (ICC 0.41-0.89) and intra-examiner (ICC 0.43-0.87) reliability. For each test, inter- and intra-examiner reliabilities at intra- and extraoral sites were similar. No significant differences between right and left sides were found intraorally. We conclude that inter- and intra-examiner reliabilities of most QST measures are acceptable for assessing somatosensory function in the orofacial region.
德国神经病理性疼痛研究网络 (DFNS) 推荐了一种包含 13 项定量感觉测试 (QST) 措施的方案，用于检测体感异常。可靠性是一个重要的科学属性，已经对皮肤 QST 进行了充分的测试。本研究评估了尚无可靠性试验报告的口腔内部位。研究了口腔内和口腔外三叉神经部位的 13 项 QST 测量的组内和组间可靠性。来自瑞典马尔默大学的 21 名健康志愿者（13 名女性和 8 名男性，平均年龄 40.4 岁，范围 24-71）参与了这项研究。两名先前接受过 DFNS QST 方案培训的独立检查者使用整个方案对参与者进行了检查。每位参与者在同一天接受两次检查，由两位检查者各检查一次（组间可靠性）。1-3 周后，一位检查者重新检查了所有参与者（组内可靠性）。测量在右侧脸颊皮肤、舌尖和上颌前磨牙区牙龈黏膜双侧进行。使用组内相关系数 (ICC) 或 Kappa 计算变异。大多数测试具有可接受至优秀的组间（ICC 0.41-0.89）和组内（ICC 0.43-0.87）可靠性。对于每项测试，口腔内和口腔外部位的组间和组内可靠性相似。口腔内没有发现左右侧之间的显著差异。我们得出结论，大多数 QST 测量的组内和组间可靠性可接受，可用于评估口腔区域的体感功能。
