Lamparter J, Kottler U, Cursiefen C, Pfeiffer N, Pitz S
Augenklinik und Poliklinik, Universitätsmedizin Mainz, Deutschland.
Ophthalmologe. 2010 Jun;107(6):553-7. doi: 10.1007/s00347-009-2083-1.
Morbus Morbihan is a rare disease characterized by persistent erythema and edema of the central and upper half of the face, mainly restricted to the forehead, glabella, eyelids, nose and cheeks. It is thought to be a rare complication of rosacea and may lead to fibrotic induration. The characteristic features are a typical clinical picture with histological alterations. Diagnosis and treatment are difficult because of the absence of specific laboratory findings and in most cases resistance to clinical therapy.We report the first case of morbus Morbihan in the ophthalmic literature. A 53-year-old woman complained of erythematous and edematous eyelids which caused a significant visual field defect for 4 years. The typical clinical picture, histological findings and the exclusion of several differential diagnoses led to the diagnosis of morbus Morbihan. Oral rosacea treatment did not result in any improvement, therefore, eyelid reduction surgery followed by lymphatic drainage was performed. Apart from cosmetic improvement a significant reduction of visual field defects was observed postoperatively.
莫比汉病是一种罕见疾病,其特征为面部中上部持续出现红斑和水肿,主要局限于前额、眉间、眼睑、鼻子和脸颊。它被认为是酒渣鼻的一种罕见并发症,可能导致纤维化硬结。其特征表现为典型的临床症状伴有组织学改变。由于缺乏特异性实验室检查结果,且在大多数情况下对临床治疗耐药,诊断和治疗都很困难。我们报告眼科文献中首例莫比汉病病例。一名53岁女性主诉眼睑出现红斑和水肿并导致显著视野缺损4年。典型的临床症状、组织学检查结果以及排除多种鉴别诊断后确诊为莫比汉病。口服治疗酒渣鼻的药物未见任何改善,因此,先进行了眼睑缩小手术,随后进行了淋巴引流。术后除了外观改善外,还观察到视野缺损显著减少。