Scheibler F, Finger R P, Grosselfinger R, Dintsios C-M
Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen, Köln, Deutschland.
Ophthalmologe. 2010 Mar;107(3):235-40. doi: 10.1007/s00347-009-2037-7.
Considering patients' values and preferences in comparative effectiveness research (CER) is one of the main challenges in ophthalmology (value-based medicine). This article defines core terms in CER. The concept of patient-relevant (or patient-important) outcomes is distinguished from patient-reported outcomes (PRO) by means of examples in the field of ophthalmology. In order to be able to give a consistant recommendation if an intervention leads to conflicting results for different outcomes (trade-off), a ranking of outcomes will be necessary. Examples of studies in glaucoma patients are provided that demonstrate the possibilities of ranking of outcomes based on patient preferences.
在比较效果研究(CER)中考虑患者的价值观和偏好是眼科(基于价值的医学)面临的主要挑战之一。本文定义了CER中的核心术语。通过眼科领域的实例,将患者相关(或患者重要)结局的概念与患者报告结局(PRO)区分开来。为了在一种干预措施对不同结局产生相互矛盾的结果(权衡)时能够给出一致的建议,有必要对结局进行排序。文中提供了青光眼患者的研究实例,展示了根据患者偏好对结局进行排序的可能性。