溶菌酶抗真菌活性的研究。

Study of antimycotic activity of lyticase.

作者信息

Sachivkina N P, Kravtsov E G, Vasilyeva E A, Anokhina I V, Dalin M V

机构信息

Department of Microbiology and Virology, Russian University of Peoples' Friendship, Moscow, Russia.

出版信息

Bull Exp Biol Med. 2009 Aug;148(2):214-6. doi: 10.1007/s10517-009-0665-1.

DOI:10.1007/s10517-009-0665-1

PMID:20027332

Abstract

Laboratory studies of lyticase (enzymatic drug) as an antimycotic agent were carried out. The enzyme reduced optical density of Candida albicans test culture, inhibited adhesion of yeast-like fungi on vaginal epitheliocytes, stimulated the formation of germinative tubes, and made Candida albicans more available for phagocytosis.

摘要

开展了溶菌酶（酶类药物）作为抗真菌剂的实验室研究。该酶降低了白色念珠菌测试培养物的光密度，抑制了酵母样真菌在阴道上皮细胞上的黏附，刺激了芽管的形成，并使白色念珠菌更易被吞噬。