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美国纽约都会区应对 2009 年大流行(H1N1)的实验室应急反应

Laboratory surge response to pandemic (H1N1) 2009 outbreak, New York City metropolitan area, USA.

机构信息

North Shore-Long Island Jewish Health System Laboratories, Manhasset, New York, USA.

出版信息

Emerg Infect Dis. 2010 Jan;16(1):8-13. doi: 10.3201/eid1601.091167.

DOI:10.3201/eid1601.091167
PMID:20031036
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2874380/
Abstract

The North Shore-Long Island Jewish Health System Laboratories serve 15 hospitals and affiliated regional physician practices in the New York City metropolitan area, with virus testing performed at a central reference laboratory. The influenza A pandemic (H1N1) 2009 outbreak began in this area on April 24, 2009, and within weeks respiratory virus testing increased 7.5 times. In response, laboratory and client service workforces were increased, physical plant build-out was completed, testing paradigms were converted from routine screening tests and viral culture to a high-capacity molecular assay for respiratory viruses, laboratory information system interfaces were built, and same-day epidemiologic reports were produced. Daily review by leadership of data from emergency rooms, hospital facilities, and the Health System Laboratories enabled real-time management of unfolding events. The ability of System laboratories to rapidly increase to high-volume comprehensive diagnostics, including influenza A subtyping, provided key epidemiologic information for local and state public health departments.

摘要

北岸 - 长岛犹太卫生系统实验室为纽约市大都市区的 15 家医院和附属区域医师执业机构提供服务,病毒检测在中央参考实验室进行。2009 年 4 月 24 日,甲型 H1N1 流感大流行在该地区爆发,数周内呼吸道病毒检测增加了 7.5 倍。作为回应,增加了实验室和客户服务人员,完成了工厂扩建,将检测模式从常规筛查检测和病毒培养转换为高容量的呼吸道病毒分子检测,建立了实验室信息系统接口,并生成了当日的流行病学报告。领导层每天对来自急诊室、医院设施和卫生系统实验室的数据进行审查,以便实时管理正在发生的事件。系统实验室能够迅速增加到高容量的综合诊断能力,包括甲型流感亚型鉴定,为当地和州公共卫生部门提供了关键的流行病学信息。

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