Institut National de la Sante et de la Recherche Medicale Unite 914, Paris, France.
Emerg Infect Dis. 2010 Jan;16(1):35-40. doi: 10.3201/eid1601.090852.
To assess dissemination of OXA-23-producing strains of Acinetobacter baumannii, we obtained 20 carbapenem-resistant, OXA-23-producing isolates from different regions. Their clonal relationship was assessed by pulsed-field gel electrophoresis and multilocus sequence typing. We identified 8 sequence types, including 4 novel types. All except 2 strains belonged to 2 main European clonal lineages. The blaOXA-23 gene was either located on the chromosome or on plasmids and associated with 4 genetic structures.
为了评估产 OXA-23 型鲍曼不动杆菌的传播情况，我们从不同地区获得了 20 株耐碳青霉烯、产 OXA-23 的分离株。通过脉冲场凝胶电泳和多位点序列分型评估了它们的克隆关系。我们鉴定了 8 种序列类型，包括 4 种新型。除了 2 株以外，所有菌株都属于 2 个主要的欧洲克隆谱系。blaOXA-23 基因要么位于染色体上，要么位于质粒上，并与 4 种遗传结构相关。
