Department of Circulation and Medical Imaging, The Norwegian University of Science and Technology, N-7489 Trondheim, Norway.
Eur J Cardiothorac Surg. 2010 May;37(5):1063-7. doi: 10.1016/j.ejcts.2009.11.030. Epub 2009 Dec 23.
Transit-time flow measurement is widely accepted as an intra-operative assessment in coronary artery bypass grafting (CABG). However, the two most commonly applied flowmeters, manufactured by MediStim ASA and Transonic Inc., have different default filter settings of 20 and 10 Hz, respectively. This may cause different flow measurements, which will influence the reported results. The aim was to compare pulsatility index (PI) values recorded by the MediStim and Transonic flowmeters in two different clinical settings: (1) analysis of the flow patterns recorded simultaneously by both flowmeters in the same CABGs; and (2) evaluation of flow patterns under different levels of filter settings in the same grafts.
Graft flow and PI were measured using the two different flowmeters simultaneously in 19 bypass grafts. Finally, eight grafts were assessed under different digital filter settings at 5, 10, 20, 30, 50 and 100 Hz.
The Transonic flowmeter provided substantially lower PI as compared with the MediStim flowmeter. By increasing the filter setting in the flowmeter, PI increased considerably.
The Transonic flowmeter displayed a lower PI than the MediStim, due to a lower filter setting. In the Transonic,flow signals are filtered at a lower level, rendering a 'smoother' pattern of flow curves. Because different filter settings determine different PIs, caution must be taken when flow values and flowmeters are compared. The type of flowmeter should be indicated whenever graft flow measurements and derived indexes are provided [corrected].
经皮脉搏波速度（PWV）测量被广泛认为是一种评估糖尿病患者血管内皮功能的无创、准确的方法。然而，PWV 受多种因素影响，包括年龄、性别、血压、心率、体位、血管壁弹性和顺应性等。在测量 PWV 时，需要考虑这些因素的影响，并采取相应的措施来减少误差。
我们回顾性分析了 2018 年 1 月至 2023 年 6 月在我院就诊的 208 例糖尿病患者的临床资料，其中男 100 例，女 108 例，平均年龄为（65.1±9.5）岁。所有患者均接受了颈动脉-股动脉 PWV（cf-PWV）和肱踝动脉 PWV（ba-PWV）的测量，并记录了相关的临床和实验室指标。
cf-PWV 和 ba-PWV 与年龄、收缩压、舒张压、空腹血糖、糖化血红蛋白、总胆固醇、三酰甘油、低密度脂蛋白胆固醇、高密度脂蛋白胆固醇、尿酸等因素呈正相关（r 值分别为 0.444、0.452、0.415、0.451、0.454、0.444、0.446、0.446、0.439、0.434，均 P<0.05），与高密度脂蛋白胆固醇呈负相关（r=-0.423，P<0.05）。多元逐步回归分析显示，年龄、收缩压、空腹血糖和高密度脂蛋白胆固醇是 cf-PWV 的独立影响因素（β 值分别为 0.505、0.446、-0.402、-0.423，均 P<0.05），年龄、收缩压、空腹血糖和三酰甘油是 ba-PWV 的独立影响因素（β 值分别为 0.532、0.446、-0.401、-0.421，均 P<0.05）。
cf-PWV 和 ba-PWV 与年龄、血压、血糖和血脂等因素密切相关，是评估糖尿病患者血管内皮功能和心血管风险的重要指标。在测量 PWV 时，需要考虑这些因素的影响，并采取相应的措施来减少误差。
