帕米膦酸二钠治疗幼年皮肌炎患者泛发性钙化完全消退。
Complete resolution of universal calcinosis in a patient with juvenile dermatomyositis using pamidronate.
机构信息
Department of Rheumatology, Ben Aknoun Hospital, rue des Deux-Bassins, Ben Aknoun, 16300 Algiers, Algeria.
出版信息
Joint Bone Spine. 2010 Jan;77(1):70-2. doi: 10.1016/j.jbspin.2009.04.011. Epub 2009 Dec 23.
PMID:20031471
Abstract
A 14-year-old girl with juvenile dermatomyositis developed extensive and debilitating calcinosis, unresponsive to colchicine, while muscle involvement subsided. Pamidronate (2mg/kg/year) produced dramatic improvement of pain and function within 2 months and calcinosis had completely resolved by 2 years. No new calcifications have been noted with a 5-year follow-up.
摘要
一位 14 岁的幼年皮肌炎女孩出现广泛且衰弱的钙化，对秋水仙碱治疗无反应，而肌肉受累减轻。帕米膦酸二钠（2mg/kg/年）治疗 2 个月内疼痛和功能显著改善，2 年内钙化完全消退。5 年随访未发现新的钙化。
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