Beigelman-Aubry C, Hill C, Boulanger X, Brun Al, Leclercq D, Golmard Jl, Grenier Pa, Lucidarme O
Service de Radiologie, Hôpital Pitié-Salpêtrière, AP-HP, Université Pierre et Marie Curie, 47-83, boulevard de l'Hôpital, 75651 Paris cedex 13.
J Radiol. 2009 Dec;90(12):1843-9. doi: 10.1016/s0221-0363(09)73590-5.
To determine the performance of a CAD system for lung nodules with ground glass opacity component on multidetector-row CT. Materials and methods. The CT examinations of 17 patients with at least one persistent subsolid nodule were reviewed. A first non-blinded consensus review by two expert radiologists resulted in the detection of 104 subsolid nodules larger than 3 mm (74 nodules of ground glass attenuation and 30 mixed nodules with solid and ground glass components). The results from this review were used as a gold standard to determine the performances of the CAD system and 3 independent clinical radiologists involved with the primary interpretations.
The sensitivity of the CAD system for the detection of ground glass opacities and mixed nodules was 53% and 73% respectively. These values were not statistically different from the values for the 3 independent observers (42-66% for ground glass opacities and 63-80% for mixed nodules). The sensitivity of each observer significantly increased when the nodules detected by the CAD system were added to those detected by each observer (p<0.0001).
A CAD system has a potential impact on the detection rate of subsolid nodules by radiologists.
确定计算机辅助检测（CAD）系统在多排螺旋CT上对含磨玻璃密度成分的肺结节的性能表现。材料与方法。回顾性分析17例至少有一个持续性亚实性结节患者的CT检查资料。两位专家放射科医生进行首次非盲法一致性阅片，共检测出104个直径大于3mm的亚实性结节（74个磨玻璃密度结节和30个实性与磨玻璃成分混合的结节）。此次阅片结果用作金标准，以确定CAD系统及3名参与初步解读的独立临床放射科医生的性能表现。
CAD系统检测磨玻璃密度结节及混合结节的敏感度分别为53%和73%。这些数值与3名独立观察者的数值无统计学差异（磨玻璃密度结节为42%-66%，混合结节为63%-80%）。当将CAD系统检测出的结节添加到每位观察者检测出的结节中时，每位观察者的敏感度均显著提高（p<0.0001）。
CAD系统对放射科医生检测亚实性结节的检出率有潜在影响。
