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穗花杉双黄酮苷,来源于鹅耳枥果实。

A chalcone glycoside from the fruits of Sorbus commixta Hedl.

机构信息

Department of Bionanochemistry, School of Natural Sciences, Wonkwang University, Iksan, Chonbuk 570-749, Korea.

出版信息

Molecules. 2009 Dec 16;14(12):5323-7. doi: 10.3390/molecules14125323.

DOI:10.3390/molecules14125323
PMID:20032895
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6255035/
Abstract

Sorbus commixta Hedl. (Rosaceae) has been traditionally used in oriental countries for the treatment of asthma and other bronchial disorders. In this study, a chalcone glycoside was isolated from the ethyl acetate extract of the fruits of this plant. The compound was identified as neosakuranin based on the spectroscopic analysis and comparison with literature data. This is the first report of isolation of neosakuranin from Sorbus commixta.

摘要

稠李(蔷薇科)在东方国家传统上被用于治疗哮喘和其他支气管疾病。在这项研究中,从该植物果实的乙酸乙酯提取物中分离出一种查尔酮糖苷。根据光谱分析和与文献数据的比较,该化合物被鉴定为新樱草素。这是首次从稠李中分离出新樱草素的报道。

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本文引用的文献

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Inhibition of protein tyrosine phosphatase 1B by lupeol and lupenone isolated from Sorbus commixta.从混合花楸中分离得到的羽扇豆醇和羽扇豆酮对蛋白酪氨酸磷酸酶 1B 的抑制作用。
J Enzyme Inhib Med Chem. 2009 Aug;24(4):1056-9. doi: 10.1080/14756360802693312.
2
Antioxidative activity of the hydrolytic enzyme treated Sorbus commixta Hedl. and its inhibitory effect on matrix metalloproteinase-1 in UV irradiated human dermal fibroblasts.水解酶处理的花楸果实的抗氧化活性及其对紫外线照射的人皮肤成纤维细胞中基质金属蛋白酶-1的抑制作用。
Arch Pharm Res. 2007 Sep;30(9):1116-23. doi: 10.1007/BF02980246.
3
Methanol extract of Sorbus commixta cortex prevents vascular inflammation in rats with a high fructose-induced metabolic syndrome.
Evid Based Complement Alternat Med. 2020 Feb 13;2020:1021258. doi: 10.1155/2020/1021258. eCollection 2020.
4
water extract induces apoptotic cell death via a ROS-dependent pathway.水提取物通过活性氧依赖途径诱导细胞凋亡性死亡。
Oncol Lett. 2018 Oct;16(4):4193-4200. doi: 10.3892/ol.2018.9217. Epub 2018 Jul 25.
5
Neuroprotective Fatty Acids from the Stem Bark of Sorbus commixta.花楸茎皮中的神经保护脂肪酸
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花楸皮甲醇提取物可预防高果糖诱导的代谢综合征大鼠的血管炎症。
Am J Chin Med. 2007;35(2):265-77. doi: 10.1142/S0192415X07004801.
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Anti-inflammatory activity of flavonoids from Populus davidiana.来自山杨的黄酮类化合物的抗炎活性。
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J Nat Prod. 2006 Aug;69(8):1215-7. doi: 10.1021/np0505216.
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