National Center for Natural Products Research, Research Institute of Pharmaceutical Sciences, School of Pharmacy, The University of Mississippi, University, Mississippi, USA.
Clin Pharmacol Ther. 2010 Feb;87(2):175-86. doi: 10.1038/clpt.2009.287. Epub 2009 Dec 23.
Whether they are being taken as dietary supplements by the general public or being evaluated in a clinical study, the authenticity of botanical products is a matter of paramount concern. Botanical specimens and the dietary supplements derived from them can vary in quality and in chemical constituent profiles because of a number of factors. Subtle variations in botanical specimens are known to have profound effects on the quality, efficacy, and safety of botanical dietary supplements and can potentially alter the results of clinical studies that rely on these materials. A complete array of authentication and evaluation tools can be utilized to provide a well-rounded scientific approach to the authentication of botanical products. It is vital that the authenticity of botanical supplements be established using appropriate analysis tools regardless of whether the end products are being considered for evaluation in clinical studies or are being developed for the consumer market.
无论是作为一般公众的膳食补充剂，还是在临床研究中进行评估，植物药产品的真实性都是至关重要的。由于多种因素，植物标本和从中提取的膳食补充剂在质量和化学成分特征方面可能存在差异。众所周知，植物标本的细微变化会对植物药膳食补充剂的质量、功效和安全性产生深远影响，并可能改变依赖这些材料的临床研究的结果。可以利用一系列全面的鉴定和评估工具，为植物药产品的鉴定提供全面的科学方法。无论最终产品是考虑用于临床研究评估，还是开发用于消费者市场，都必须使用适当的分析工具来确定植物补充剂的真实性，这一点至关重要。
