National Center for Natural Products Research, Research Institute of Pharmaceutical Sciences, University of Mississippi, University, MS 38677, USA.
Planta Med. 2011 May;77(8):851-7. doi: 10.1055/s-0030-1250583. Epub 2010 Dec 2.
Hoodia gordonii, a succulent plant growing in African arid regions, is used as a botanical dietary supplement for weight loss. The increasing concerns on the quality and safety of Hoodia products call for the needs of more science-based information, as well as objective and efficient tools for inspection. In the present study, NMR fingerprinting and multivariate analysis techniques were applied for the identification, discrimination, and quality analysis of Hoodia plant materials and commercial products. Four Hoodia species, namely H. gordonii (five authenticated samples), H. currorii (one authenticated sample), H. parviflora (three authenticated samples), and H. rushii (one authenticated sample), were investigated; the chemicals and characteristic spectral signals that made most contributions for their differentiations were revealed. With the aid of NMR fingerprint analysis, ten Hoodia products sold on the dietary supplement market were assessed for their chemical composition and quality. The study demonstrated that the NMR fingerprinting approach could be a promising and efficient tool for the authentication of botanicals.
霍地仙，一种生长在非洲干旱地区的肉质植物，被用作减肥的植物性膳食补充剂。对霍地仙产品质量和安全性的日益关注，要求提供更多基于科学的信息，以及客观有效的检测工具。本研究应用 NMR 指纹图谱和多元分析技术，对霍地仙植物材料和商业产品进行鉴定、区分和质量分析。研究了四种霍地仙物种，即霍地仙（五个已鉴定样本）、霍地仙（一个已鉴定样本）、霍地仙（三个已鉴定样本）和霍地仙（一个已鉴定样本），揭示了对其区分贡献最大的化学成分和特征谱信号。借助 NMR 指纹分析，评估了市场上销售的十种膳食补充剂用霍地仙产品的化学成分和质量。研究表明，NMR 指纹图谱方法可能是一种有前途和有效的植物鉴别工具。
