Leite C, Goodwin J W, Sinkovics J G, Baker L H, Benjamen R
Cancer. 1977 Nov;40(5):2010-4. doi: 10.1002/1097-0142(197711)40:5<2010::aid-cncr2820400504>3.0.co;2-1.
Malignant fibrous histiocytoma is a rare tumor, which constitutes 3-4% of the soft tissue sarcomas. It occurs with maximum frequency in the sixth and seventh decades of life and has a distinct male preponderance. In two-thirds of the patients an extremity is the primary site and approximately one-half develop local recurrences and one-half, distant metastases. Response to combination chemotherapy occurred in 33%, a rate similar to that seen in other sarcomas.
恶性纤维组织细胞瘤是一种罕见肿瘤，占软组织肉瘤的3% - 4%。它在60到70岁时发病率最高，男性明显居多。三分之二的患者以四肢为原发部位，约一半患者出现局部复发，另一半出现远处转移。联合化疗的有效率为33%，这一比率与其他肉瘤相似。
