Tewfik H H, Tewfik F A, Latourette H B
J Surg Oncol. 1981;16(2):189-97. doi: 10.1002/jso.2930160211.
Twenty-four patients with malignant fibrous histiocytoma are being analyzed: 54.2% occurred in the sixth, seventh, and eighth decades of life; 45.8% were located in the extremities. This is a soft tissue sarcoma noted for its pleomorphic histologic appearance. It is postulated that the origin cell is a histiocyte. The local recurrence of metastatic potential of this tumor is difficult to predict from its histological features. Local recurrence after complete excision is frequent. Also, there is a high incidence of distant metastases. Wide local excision with a wide margin around the tumor is the most important treatment modality. The use of postoperative radiotherapy and chemotherapy needs to be evaluated.
正在分析24例恶性纤维组织细胞瘤患者：54.2%发生在60、70和80岁年龄段；45.8%位于四肢。这是一种软组织肉瘤，以其多形性组织学表现为特征。据推测，起源细胞是组织细胞。该肿瘤的局部复发或转移潜能很难从其组织学特征来预测。完整切除术后局部复发很常见。此外，远处转移的发生率也很高。肿瘤周围进行广泛边缘的广泛局部切除是最重要的治疗方式。术后放疗和化疗的使用需要评估。
