Maslyukov P M, Korzina M B, Emanuilov A I, Shilkin V V
Department of Normal Physiology with Biophysics, Yaroslavl State Medical Academy, Yaroslavl, Russia.
Neurosci Behav Physiol. 2010 Feb;40(2):143-7. doi: 10.1007/s11055-009-9247-y. Epub 2009 Dec 22.
The neurotransmitter composition of neurons in the cranial cervical ganglion (CCG) and celiac ganglia (CG) in rats of different ages (neonatal, 10, 12, 30, and 60 days) was studied by immunohistochemical methods. The results showed that most neurons in these sympathetic ganglia contain tyrosine hydroxylase (TH). Most TH-positive neurons were also neuropeptide Y (NPY)-positive. In all ganglia, the proportions of neurons containing NPY increased from the moment of birth to the end of the first month of life. In the CG, NPY was present in a significantly greater proportion of neurons than in the CCG. Substance P, vasoactive intestinal peptide, and choline acetyltransferase were present in occasional neurons in the CCG and CG from birth. There was no change in the proportion of this type of neuron with age. Definitive establishment of the neurotransmitter composition in the sympathetic ganglia studied here occurred by the end of the first month of life.
采用免疫组织化学方法研究了不同年龄（新生、10天、12天、30天和60天）大鼠颈上神经节（CCG）和腹腔神经节（CG）中神经元的神经递质组成。结果显示，这些交感神经节中的大多数神经元含有酪氨酸羟化酶（TH）。大多数TH阳性神经元也是神经肽Y（NPY）阳性。在所有神经节中，含NPY的神经元比例从出生时到出生后第一个月末均增加。在CG中，NPY存在于神经元中的比例明显高于CCG。出生时，P物质、血管活性肠肽和胆碱乙酰转移酶偶尔存在于CCG和CG的神经元中。这类神经元的比例不随年龄变化。此处研究的交感神经节中神经递质组成在出生后第一个月末最终确定。
