Department of Nuclear Medicine, Kanazawa University Hospital, 13-1 Takara-machi, Kanazawa 920-8641, Japan.
Ann Nucl Med. 2010 Feb;24(2):99-105. doi: 10.1007/s12149-009-0331-8. Epub 2009 Dec 25.
The Japanese Society of Nuclear Medicine (JSNM) working group has created a myocardial perfusion imaging database applicable to standard acquisition protocol. The aim of this study is to validate the diagnostic accuracy of the common normal database compared with the expert interpretation of each institute.
Five institutions participated in this study and used different acquisition settings which included 360 degrees /180 degrees rotation, camera configuration and camera orbits. The software and its version used in each institution also varied. The working group database was applied to detect the culprit coronary territory from a total of 166 patients with coronary artery disease (CAD) and 145 patients with low-likelihood of CAD.
When summed stress score > or =4 was defined as significant abnormality, overall sensitivity, specificity and accuracy of patient-based analysis were 77, 72 and 75%, respectively, based on quantitative analysis using the common database, whereas those by institutional visual expert reading were 72, 79 and 75%, respectively.
The common database, which was created by a multi-center working group and separated between male/female with 180/360 degrees acquisitions, demonstrated comparable diagnostic accuracy to expert interpretation by each institute, and it may be applicable to multi-center studies.
日本核医学会（JSNM）工作组创建了一个适用于标准采集方案的心肌灌注成像数据库。本研究的目的是验证常见正常数据库的诊断准确性与各机构专家解读的比较。
五家机构参与了这项研究，并使用了不同的采集设置，包括 360 度/180 度旋转、相机配置和相机轨道。各机构使用的软件及其版本也有所不同。工作组数据库应用于检测总共 166 例冠心病（CAD）患者和 145 例低 CAD 可能性患者的罪犯冠状动脉区域。
当总和应激评分≥4 定义为显著异常时，基于共同数据库的定量分析，患者为基础的分析的总体敏感性、特异性和准确性分别为 77%、72%和 75%，而机构视觉专家阅读的分别为 72%、79%和 75%。
由多中心工作组创建并按男性/女性、180/360 度采集进行分组的共同数据库，显示出与各机构专家解读相当的诊断准确性，可能适用于多中心研究。
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