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美国过度膀胱活动症的经济成本。

Economic costs of overactive bladder in the United States.

机构信息

Abt Bio-Pharma Solutions, Inc., Lexington, Massachusetts 02421, USA.

出版信息

Urology. 2010 Mar;75(3):526-32, 532.e1-18. doi: 10.1016/j.urology.2009.06.096. Epub 2009 Dec 29.

Abstract

OBJECTIVES

To calculate, from a societal perspective, current direct (medical and nonmedical) and indirect costs of overactive bladder (OAB) in the United States and project them to future years. Existing cost assessments of OAB in the United States are incomplete and outdated.

METHODS

A prevalence-based model was developed incorporating age- and sex-specific OAB prevalence rates, usage data, and productivity data. On the basis of the information gathered from the recent 5 years of the medical literature, practice guidelines, Medicare and managed care fee schedules, and expert panel input, the annual per capita and total US costs were calculated for 2007. US census population forecasts were used to project the costs of OAB to 2015 and 2020.

RESULTS

In 2007, average annual per capita costs of OAB were $1925 ($1433 in direct medical, $66 in direct nonmedical, and $426 in indirect costs). Applying these costs to the 34 million people in the United States with OAB results in total national costs of $65.9 billion (billion = 1000 million), ($49.1 billion direct medical, $2.3 billion direct nonmedical, and $14.6 billion indirect). Average annual per capita costs in 2015 and 2020 would be $1944 and $1969 and total national costs would be $76.2 billion and $82.6 billion, respectively.

CONCLUSIONS

These data suggest that the economic burden of OAB is about 5-fold higher than older, noncomprehensive estimates. These costs are higher than previously published data for the United States and Europe because this analysis relies on more current data, real world age- and sex-specific treatment patterns and costs, and includes a more complete set of cost components.

摘要

目的

从社会角度计算美国目前过度膀胱症(OAB)的直接(医疗和非医疗)和间接成本,并预测未来几年的成本。美国现有的 OAB 成本评估不完整且已过时。

方法

采用基于流行率的模型,纳入了年龄和性别特异性 OAB 流行率、使用率数据和生产力数据。根据最近 5 年的医学文献、实践指南、医疗保险和管理式医疗费用表以及专家小组的意见收集的信息,计算了 2007 年的美国每年人均和总体成本。使用美国人口普查的预测数据,将 OAB 的成本预测到 2015 年和 2020 年。

结果

2007 年,OAB 的平均每年人均成本为 1925 美元(直接医疗费用为 1433 美元,直接非医疗费用为 66 美元,间接费用为 426 美元)。将这些成本应用于美国 3400 万患有 OAB 的人中,导致全国总成本为 659 亿美元(十亿= 10 亿)(直接医疗费用为 491 亿美元,直接非医疗费用为 23 亿美元,间接费用为 146 亿美元)。2015 年和 2020 年的平均每年人均成本将分别为 1944 美元和 1969 美元,全国总成本将分别为 762 亿美元和 826 亿美元。

结论

这些数据表明,OAB 的经济负担比旧的、非全面的估计高 5 倍。这些成本高于以前在美国和欧洲发表的数据,因为该分析依赖于更当前的数据、真实世界的年龄和性别特异性治疗模式和成本,并包括更完整的成本组成部分。

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