Department of Obstetrics & Gynecology, University of Khartoum, Sudan.
Biol Trace Elem Res. 2010 Dec;137(3):255-61. doi: 10.1007/s12011-009-8586-4. Epub 2009 Dec 29.
Anaemia is a widespread problem in many parts of the world especially in tropic areas. Among pregnant women, it has negative consequences on maternal and perinatal outcomes. A cross-sectional study was conducted to investigate the prevalence of anaemia, iron, zinc and copper deficiencies among pregnant women in Wad Medani hospital, central Sudan and to examine the relationship of these micronutrients with haemoglobin (Hb) levels. One hundred four (52.5%) out of 200 pregnant women had anaemia (Hb < 11 gm/dl) and 3 (1.5) % had severe anaemia (Hb < 7 gm/dl). Iron deficiency (S-ferritin < 15 µg/l), iron deficiency anaemia (<11 gm/dl and S-ferritin < 15 µg/l) were prevalent in 25 (12.5%) and 13 (6.5%) of these women, respectively. Ninety (45.0%) and eight (4.0%) of these women had zinc (<80 µg/ml) and copper (<80 µg/ml) deficiency, respectively. In 24 (12.0%) of these women, there were ≥2 deficiencies of these elements. S-copper was not [corrected] significantly lower in patients with anaemia. While age, parity, gestational age, ferritin, zinc and copper were not predictors for anaemia, women who practiced pica were at higher risk for anaemia (OR = 3.4, 95% CI = 1.4-7.9, P = 0.004). Gestational age was significantly inversely correlated with haemoglobin (r = 0.161, P = 0.03), S-ferritin (r = 0.285, P = 0.001) and S-zinc (r = 0.166, P = 0.02). Thus, dietary and supplement interventions are required to prevent and control anaemia in this setting. Further research is needed.
贫血是世界上许多地区,尤其是热带地区普遍存在的问题。在孕妇中,它对母婴和围产期结局有负面影响。本研究旨在调查苏丹中部瓦德梅达尼医院孕妇贫血、铁、锌和铜缺乏的流行情况,并探讨这些微量营养素与血红蛋白(Hb)水平的关系。在 200 名孕妇中,有 104 名(52.5%)患有贫血(Hb < 11g/dl),3 名(1.5%)患有严重贫血(Hb < 7g/dl)。铁缺乏(S-铁蛋白<15μg/l)、缺铁性贫血(Hb < 11g/dl 和 S-铁蛋白<15μg/l)在这些女性中分别有 25 名(12.5%)和 13 名(6.5%)。90 名(45.0%)和 8 名(4.0%)这些女性分别有锌(<80μg/ml)和铜(<80μg/ml)缺乏。在这些女性中,有 24 名(12.0%)存在≥2 种元素缺乏。贫血患者的 S-铜并没有显著降低。虽然年龄、产次、孕龄、铁蛋白、锌和铜不是贫血的预测因素,但有食癖的女性患贫血的风险更高(OR=3.4,95%CI=1.4-7.9,P=0.004)。孕龄与血红蛋白(r=0.161,P=0.03)、S-铁蛋白(r=0.285,P=0.001)和 S-锌(r=0.166,P=0.02)呈显著负相关。因此,需要进行饮食和补充干预以预防和控制该地区的贫血。需要进一步研究。