Department of Food Science, College of Life Sciences, National Taiwan Ocean University, Keelung 20224, Taiwan.
Institute of Food Safety and Risk Management, College of Life Sciences, National Taiwan Ocean University, Keelung 20224, Taiwan.
Nutrients. 2022 Nov 20;14(22):4918. doi: 10.3390/nu14224918.
Zinc is an essential trace element, and anemia is the most common blood disorder. The association of zinc with anemia may be divided into three major forms: (1) zinc deficiency contributing to anemia, (2) excess intake of zinc leading to anemia, and (3) anemia leading to abnormal blood-zinc levels in the body. In most cases, zinc deficiency coexists with iron deficiency, especially in pregnant women and preschool-age children. To a lesser extent, zinc deficiency may cooperate with other factors to lead to anemia. It seems that zinc deficiency alone does not result in anemia and that it may need to cooperate with other factors to lead to anemia. Excess intake of zinc is rare. However, excess intake of zinc interferes with the uptake of copper and results in copper deficiency that leads to anemia. Animal model studies indicate that in anemia, zinc is redistributed from plasma and bones to the bone marrow to produce new red blood cells. Inadequate zinc status (zinc deficiency or excess) could have effects on anemia; at the same time, anemia could render abnormal zinc status in the body. In handling anemia, zinc status needs to be observed carefully, and supplementation with zinc may have preventive and curative effects.
锌是一种必需的微量元素，而贫血是最常见的血液疾病。锌与贫血的关系可分为三种主要形式：（1）锌缺乏导致贫血，（2）锌摄入过多导致贫血，（3）贫血导致体内血液锌水平异常。在大多数情况下，锌缺乏与铁缺乏并存，尤其是孕妇和学龄前儿童。在较小程度上，锌缺乏可能与其他因素合作导致贫血。似乎单纯的锌缺乏不会导致贫血，它可能需要与其他因素合作导致贫血。锌摄入过多很少见。然而，锌摄入过多会干扰铜的摄取，导致铜缺乏，从而导致贫血。动物模型研究表明，在贫血中，锌从血浆和骨骼重新分配到骨髓中，以产生新的红细胞。锌状态不足（锌缺乏或过多）可能对贫血有影响；同时，贫血也可能导致体内锌状态异常。在处理贫血时，需要仔细观察锌的状态，补充锌可能具有预防和治疗作用。
