Rastogi Subodh Kumar, Pandey Amit, Tripathi Sachin
Epidemiology Division, Indian Institute of Toxicology Research, Post Box No. 80, Mahatma Gandhi Marg, Uttar Pradesh, India.
Indian J Occup Environ Med. 2008 Dec;12(3):132-5. doi: 10.4103/0019-5278.44695.
In a cross-sectional study, a random sample of 197 male workers drawn from different sections of 10 leather tanneries in Kanpur were selected for the assessment of health risks. A control group comprising of 117 male subjects belonging to a similar age group and socioeconomic strata, who never had any occupational exposure in the leather tanneries, were also examined for the comparison purpose. The findings revealed a significantly higher prevalence of morbidity among the exposed workers in contrast to that observed in the controls (40.1% vs. 19.6%). The respiratory diseases (16.7%) were mainly responsible for a higher morbidity among the exposed workers whereas the gastrointestinal tract problems were predominant in the control group. The urinary and blood samples collected from the exposed group showed significantly higher levels of chromium, thereby reflecting the body burden of Cr in the exposed workers as a result of a high concentration of environmental Cr at the work place.
在一项横断面研究中,从坎普尔10家皮革厂不同部门随机抽取197名男性工人,以评估健康风险。还选取了一个由117名年龄相仿、社会经济阶层相同且从未在皮革厂有过任何职业暴露的男性受试者组成的对照组进行比较。研究结果显示,与对照组相比,暴露工人的发病率显著更高(40.1%对19.6%)。呼吸系统疾病(16.7%)是导致暴露工人发病率较高的主要原因,而胃肠道问题在对照组中占主导。从暴露组采集的尿液和血液样本显示铬含量显著更高,从而反映出由于工作场所环境铬浓度高,暴露工人体内的铬负荷。