• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

相似文献

1
Relationship between obesity and incident diabetes in middle-aged and older Japanese adults: the Ibaraki Prefectural Health Study.中年和老年日本成年人肥胖与新发糖尿病的关系：茨城县健康研究。
Mayo Clin Proc. 2010 Jan;85(1):36-40. doi: 10.4065/mcp.2009.0230.
2
Utility of the triglyceride level for predicting incident diabetes mellitus according to the fasting status and body mass index category: the Ibaraki Prefectural Health Study.根据空腹状态和体重指数类别，甘油三酯水平对预测糖尿病发病的效用：茨城县健康研究
J Atheroscler Thromb. 2014;21(11):1152-69. doi: 10.5551/jat.22913. Epub 2014 Jul 16.
3
Increases in body mass index, even within non-obese levels, raise the risk for Type 2 diabetes mellitus: a follow-up study in a Japanese population.体重指数增加，即使在非肥胖水平内，也会增加2型糖尿病的风险：一项日本人群的随访研究。
Diabet Med. 2005 Aug;22(8):1107-11. doi: 10.1111/j.1464-5491.2005.01602.x.
4
The dose-response relationship between body mass index and the risk of incident stage ≥3 chronic kidney disease in a general japanese population: the Ibaraki prefectural health study (IPHS).日本普通人群中体重指数与≥3期慢性肾脏病发病风险之间的剂量反应关系：茨城县健康研究（IPHS）
J Epidemiol. 2014;24(6):444-51. doi: 10.2188/jea.je20140028. Epub 2014 Jul 5.
5
Impact of obesity on incident hypertension independent of weight gain among nonhypertensive Japanese: the Ibaraki Prefectural Health Study (IPHS).肥胖对非高血压日本人群中高血压发病的影响与体重增加无关：茨城县健康研究（IPHS）。
J Hypertens. 2012 Jun;30(6):1122-8. doi: 10.1097/HJH.0b013e328352b879.
6
Risk of smoking and body mass index for incidence of diabetes mellitus in a rural Japanese population.在日本农村人口中，吸烟风险和体重指数与糖尿病发病的关系。
Prev Med. 2012 May;54(5):341-4. doi: 10.1016/j.ypmed.2012.02.016. Epub 2012 Mar 4.
7
Association of alcohol consumption with incident hypertension among middle-aged and older Japanese population: the Ibarakai Prefectural Health Study (IPHS).饮酒与日本中老年人群高血压事件的相关性：岩代市健康研究（IPHS）。
Hypertension. 2014 Jan;63(1):41-7. doi: 10.1161/HYPERTENSIONAHA.113.01585. Epub 2013 Oct 14.
8
Fasting serum glucose level and cancer risk in Korean men and women.韩国男性和女性的空腹血糖水平与癌症风险
JAMA. 2005 Jan 12;293(2):194-202. doi: 10.1001/jama.293.2.194.
9
Physical activity and incidence of diabetes: the Honolulu Heart Program.身体活动与糖尿病发病率：檀香山心脏项目
Am J Epidemiol. 1995 Feb 15;141(4):360-8. doi: 10.1093/aje/141.4.360.
10
Cigarette smoking and risk for impaired fasting glucose and type 2 diabetes in middle-aged Japanese men.中年日本男性吸烟与空腹血糖受损及2型糖尿病风险
Ann Intern Med. 2000 Aug 1;133(3):183-91. doi: 10.7326/0003-4819-133-3-200008010-00009.

引用本文的文献

1
Body Mass Index Progression, Development of Complications and Healthcare Costs Over 8 Years in UK Individuals Living With Overweight/Obesity.英国超重/肥胖个体8年期间的体重指数进展、并发症发生情况及医疗费用
Adv Ther. 2025 Sep;42(9):4626-4640. doi: 10.1007/s12325-025-03285-6. Epub 2025 Jul 28.
2
Identification of effect modifiers using a stratified Mendelian randomization algorithmic framework.使用分层孟德尔随机化算法框架鉴定效应修饰因子。
Eur J Epidemiol. 2025 Mar 12. doi: 10.1007/s10654-025-01213-0.
3
Patterns of trajectories of glycated hemoglobin, fasting plasma glucose, and body mass index until the first clinic visit: the real-world history of type 2 diabetes using repeated health checkup data of Japanese workers.首次门诊就诊前糖化血红蛋白、空腹血糖和体重指数的轨迹模式：利用日本工人的重复健康检查数据分析2型糖尿病的真实病史
Fam Pract. 2025 Feb 7;42(2). doi: 10.1093/fampra/cmae054.
4
Incidence and temporal trends in type 2 diabetes by weight status: A systematic review and meta-analysis of prospective cohort studies.按体重状况划分的 2 型糖尿病发病率及时间趋势：前瞻性队列研究的系统评价和荟萃分析。
J Glob Health. 2023 Sep 1;13:04088. doi: 10.7189/jogh.13.04088.
5
The Lifelong Health Support 10: a Japanese prescription for a long and healthy life.《终生健康支持 10：日本人的长寿健康之道》。
Environ Health Prev Med. 2022;27:23. doi: 10.1265/ehpm.22-00085.
6
Changes in subjective sleep quality in patients with type 2 diabetes who did not use Sleep agents: a cross-sectional study according to age and clinical background.未使用助眠药物的2型糖尿病患者主观睡眠质量的变化：一项根据年龄和临床背景的横断面研究。
Diabetol Int. 2021 Jun 2;13(1):142-147. doi: 10.1007/s13340-021-00516-3. eCollection 2022 Jan.
7
Social Capital as a Mediator through the Effect of Education on Depression and Obesity among the Elderly in China.社会资本在中国老年人抑郁和肥胖中作为教育影响的中介。
Int J Environ Res Public Health. 2020 Jun 4;17(11):3977. doi: 10.3390/ijerph17113977.
8
The Science of Obesity Management: An Endocrine Society Scientific Statement.肥胖管理科学：内分泌学会科学声明。
Endocr Rev. 2018 Apr 1;39(2):79-132. doi: 10.1210/er.2017-00253.
9
A Nutrition Intervention Focused on Weight Management Through Lifestyle Improvements in Prediabetic Subjects.一项通过改善生活方式对糖尿病前期患者进行体重管理的营养干预措施。
Clin Nutr Res. 2018 Jan;7(1):69-79. doi: 10.7762/cnr.2018.7.1.69. Epub 2018 Jan 2.
10
B cell-activating factor is associated with the histological severity of nonalcoholic fatty liver disease.B细胞活化因子与非酒精性脂肪性肝病的组织学严重程度相关。
Hepatol Int. 2013 Jun;7(2):539-47. doi: 10.1007/s12072-012-9345-8. Epub 2012 Feb 9.

本文引用的文献

1
[Development of a diabetes risk prediction sheet for specific health guidance].[开发用于特定健康指导的糖尿病风险预测表]
Nihon Koshu Eisei Zasshi. 2008 May;55(5):287-94.
2
Underweight as a predictor of diabetes in older adults: a large cohort study.体重过轻作为老年人糖尿病的预测指标：一项大型队列研究。
Diabetes Care. 2008 Mar;31(3):583-4. doi: 10.2337/dc07-1390. Epub 2007 Dec 10.
3
Morbidity and mortality risk associated with an overweight BMI in older men and women.老年男性和女性超重体质指数（BMI）相关的发病和死亡风险。
Obesity (Silver Spring). 2007 Jul;15(7):1827-40. doi: 10.1038/oby.2007.217.
4
Body mass index and risk of diabetes mellitus in the Asia-Pacific region.亚太地区的体重指数与糖尿病风险
Asia Pac J Clin Nutr. 2006;15(2):127-33.
5
Adiponectin--a key adipokine in the metabolic syndrome.脂联素——代谢综合征中的一种关键脂肪因子。
Diabetes Obes Metab. 2006 May;8(3):264-80. doi: 10.1111/j.1463-1326.2005.00510.x.
6
Increases in body mass index, even within non-obese levels, raise the risk for Type 2 diabetes mellitus: a follow-up study in a Japanese population.体重指数增加，即使在非肥胖水平内，也会增加2型糖尿病的风险：一项日本人群的随访研究。
Diabet Med. 2005 Aug;22(8):1107-11. doi: 10.1111/j.1464-5491.2005.01602.x.
7
Influence of gender, age and renal function on plasma adiponectin level: the Tanno and Sobetsu study.性别、年龄和肾功能对血浆脂联素水平的影响：田野和矶部研究
Eur J Endocrinol. 2005 Jul;153(1):91-8. doi: 10.1530/eje.1.01930.
8
Relationship of physical activity vs body mass index with type 2 diabetes in women.女性身体活动与体重指数与2型糖尿病的关系。
JAMA. 2004 Sep 8;292(10):1188-94. doi: 10.1001/jama.292.10.1188.
9
Improvement in Japanese clinical laboratory measurements of total cholesterol and HDL-cholesterol by the US Cholesterol Reference Method Laboratory Network.美国胆固醇参考方法实验室网络对日本临床实验室总胆固醇和高密度脂蛋白胆固醇测量结果的改善。
J Atheroscler Thromb. 2003;10(3):145-53. doi: 10.5551/jat.10.145.
10
Obesity, weight change and risks for hypertension, diabetes and hypercholesterolemia in Japanese men.日本男性的肥胖、体重变化与高血压、糖尿病和高胆固醇血症风险
Eur J Clin Nutr. 2002 Jul;56(7):601-7. doi: 10.1038/sj.ejcn.1601364.

中年和老年日本成年人肥胖与新发糖尿病的关系：茨城县健康研究。

Relationship between obesity and incident diabetes in middle-aged and older Japanese adults: the Ibaraki Prefectural Health Study.

机构信息

Ibaraki Health Plaza, Ibaraki, Japan.

出版信息

Mayo Clin Proc. 2010 Jan;85(1):36-40. doi: 10.4065/mcp.2009.0230.

DOI:10.4065/mcp.2009.0230
PMID:20042559
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2800296/
Abstract

OBJECTIVE

To investigate the age-specific relationship between body mass index (BMI) and risk of diabetes in a Japanese general population.

PARTICIPANTS AND METHODS

A cohort of Japanese men (N=19,926) and women (N=41,489) (aged 40-79 years) who under went community-based health checkups in 1993 and were free of diabetes was followed up by annual examinations with measurement of blood glucose concentrations until the end of 2006. Incident diabetes mellitus was defined as a blood glucose concentration of 126 mg/dL or greater under fasting conditions, 200 mg/dL or greater under nonfasting conditions, or diabetic medication use at baseline. Hazard ratios (HRs) for diabetes according to BMI were estimated using a Cox proportional hazard model. The model was adjusted for possible confounding variables.

RESULTS

A total of 4429 participants (7.2%) developed diabetes (2065 men and 2364 women) during a mean follow-up of 5.5 years. Compared with those with a BMI of less than 25.0, the multivariate HRs for diabetes among participants with a BMI of 30.0 or greater were 1.40 (95% confidence interval [CI], 0.89-2.20) for men aged 40 to 59 years and 1.26 (95% CI, 0.81-1.96) for men aged 60 to 79 years (P=.002 for interaction). The HRs were 2.50 (95% CI, 2.01-3.11) for women aged 40 to 59 years and 1.80 (95% CI, 1.41-2.30) for women aged 60 to 79 years (P=.04 for interaction).

CONCLUSION

The effect of obesity on the risk of diabetes is greater for middle-aged than for older adults.

摘要

目的

探讨日本一般人群中体质指数（BMI）与糖尿病风险的年龄特异性关系。

参与者和方法

1993 年，对参加社区健康检查的日本男性（N=19926）和女性（N=41489）（年龄 40-79 岁）进行了队列研究，这些人在基线时无糖尿病，并在随后的年度检查中测量血糖浓度，随访至 2006 年底。糖尿病定义为空腹血糖浓度为 126mg/dL 或更高、非空腹血糖浓度为 200mg/dL 或更高，或在基线时使用降糖药物。采用 Cox 比例风险模型估计 BMI 与糖尿病的风险比（HR）。该模型调整了可能的混杂变量。

结果

共有 4429 名参与者（7.2%）在平均 5.5 年的随访中发生了糖尿病（2065 名男性和 2364 名女性）。与 BMI 小于 25.0 的参与者相比，BMI 为 30.0 或更高的男性参与者中，年龄为 40-59 岁者糖尿病的多变量 HR 为 1.40（95%置信区间 [CI]，0.89-2.20），年龄为 60-79 岁者为 1.26（95% CI，0.81-1.96）（P=0.002 用于交互作用检验）。年龄为 40-59 岁的女性参与者的 HR 为 2.50（95% CI，2.01-3.11），年龄为 60-79 岁的女性参与者的 HR 为 1.80（95% CI，1.41-2.30）（P=0.04 用于交互作用检验）。

结论

肥胖对糖尿病风险的影响在中年人中比在老年人中更大。