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Abbott RealTime HIV-1 检测试剂对科巴思 AmpliPrep/Cobas TaqMan HIV-1 检测试剂产生“靶标未检出”结果的标本的检测结果。

Results of the Abbott RealTime HIV-1 assay for specimens yielding "target not detected" results by the Cobas AmpliPrep/Cobas TaqMan HIV-1 Test.

机构信息

Division of Clinical Microbiology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota 55905-0002, USA.

出版信息

J Clin Microbiol. 2010 Mar;48(3):969-71. doi: 10.1128/JCM.01394-09. Epub 2009 Dec 30.

DOI:10.1128/JCM.01394-09
PMID:20042629
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2832422/
Abstract

No significantly discordant results were observed between the Abbott RealTime HIV-1 assay and the COBAS AmpliPrep/COBAS TaqMan HIV-1 Test (CTM) among 1,190 unique clinical plasma specimens obtained from laboratories located in 40 states representing all nine U.S. geographic regions and previously yielding "target not detected" results by CTM.

摘要

在雅培实时 HIV-1 检测法与科巴思 Ampliprep/科巴思 TaqMan HIV-1 检测(CTM)之间,并未观察到 1190 份独特的临床血浆样本中存在显著不一致的结果,这些样本来自 40 个州的实验室,代表了美国所有九个地理区域,此前 CTM 检测结果为“靶标未检出”。

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Clin Infect Dis. 2009 Jun 1;48(11):1630-1; author reply 1631-2. doi: 10.1086/598990.
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Single-point mutations causing more than 100-fold underestimation of human immunodeficiency virus type 1 (HIV-1) load with the Cobas TaqMan HIV-1 real-time PCR assay.单点突变导致使用Cobas TaqMan HIV-1实时荧光定量PCR检测法对1型人类免疫缺陷病毒(HIV-1)载量的低估超过100倍。
J Clin Microbiol. 2009 Apr;47(4):1238-40. doi: 10.1128/JCM.02204-08. Epub 2009 Feb 4.
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