睡眠呼吸障碍与充血性心力衰竭患者的适当植入式心脏复律除颤器治疗有关。
Sleep disordered breathing is associated with appropriate implantable cardioverter defibrillator therapy in congestive heart failure patients.
机构信息
Department of Biomedical and Surgical Sciences, University of Verona, Italy.
出版信息
Clin Cardiol. 2010 Feb;33(2):E27-30. doi: 10.1002/clc.20602.
Abstract
BACKGROUND
Implantable cardioverter defibrillators (ICDs) are increasingly employed in patients affected by congestive heart failure (CHF) and sleep disordered breathing (SDB) is frequent in this population.
HYPOTHESIS
To investigate SDB prevalence and influence on appropriate ICD discharges in CHF patients.
METHODS
A total of 22 consecutive ICD patients with systolic CHF (left ventricular ejection fraction [LVEF]< 45%) were studied by polysomnography.
RESULTS
A total of 17 (77.2%) showed SDB (apnea-hypopnea index [AHI]_ 10 events/hour). After controlling for LVEF and New York Heart Association (NYHA) class, AHI and severity of hypoxia during sleep results correlated to appropriate ICD discharges (r = 0.718; P < .001, r = - 0.619; P = .003, respectively).
CONCLUSIONS
Sleep disordered breathing is frequent in ICD recipients due to left systolic ventricular dysfunction and may increase the risk of ventricular arrhythmia and appropriate ICD discharges.
摘要
背景
植入式心脏复律除颤器（ICD）越来越多地应用于充血性心力衰竭（CHF）患者，而睡眠呼吸紊乱（SDB）在这一人群中很常见。
假说
研究 SDB 的患病率及其对 CHF 患者中合适的 ICD 放电的影响。
方法
对 22 例连续的收缩性 CHF（左心室射血分数 [LVEF] <45%）的 ICD 患者进行多导睡眠图检查。
结果
共 17 例（77.2%）存在 SDB（呼吸暂停低通气指数 [AHI] > 10 次/小时）。在控制 LVEF 和纽约心脏协会（NYHA）分级后，AHI 和睡眠期间缺氧的严重程度与合适的 ICD 放电相关（r = 0.718；P <.001，r = - 0.619；P =.003）。
结论
由于左心室收缩功能障碍，ICD 受者中睡眠呼吸紊乱很常见，可能增加室性心律失常和合适的 ICD 放电的风险。
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