Bilicki Kerry L, Schermerhorn Thomas, Klocke Emily E, McMurphy Rose M, Roush James K
Department of Small Animal Medicine and Surgery, College of Veterinary Medicine, Kansas State University, Manhattan, KS 66506, USA.
Am J Vet Res. 2010 Jan;71(1):11-6. doi: 10.2460/ajvr.71.1.11.
To evaluate the accuracy of a real-time, continuous glucose monitoring system (CGMS) in healthy dogs undergoing anesthesia for elective ovariohysterectomy or orchiectomy.
10 healthy dogs undergoing routine elective surgery.
A CGMS was placed and used to obtain calculated glucose measurements before, during, and after anesthesia in each dog. Periodically, CGMS measurements were compared with concurrent measurements of glucose concentration in peripheral venous blood obtained with a portable chemistry analyzer (PCA).
CGMS-calculated glucose measurements were significantly different from PCA blood glucose measurements during most of the anesthetic period. The CGMS values differed from PCA values by > 20% in 54 of 126 (42.9%) paired measurements obtained during the anesthetic period. Hypoglycemia was evident in CGMS measurements 25 of 126 (19.8%) times during anesthesia. By comparison, only 1 incident of hypoglycemia was detected with the PCA during the same period.
Use of the CGMS for routine monitoring of interstitial glucose concentration as an indicator of blood glucose concentration during anesthesia cannot be recommended. Additional investigation is necessary to elucidate the cause of discrepancy between CGMS results and PCA data during anesthesia.
评估实时连续血糖监测系统（CGMS）在接受择期卵巢子宫切除术或睾丸切除术麻醉的健康犬中的准确性。
10只接受常规择期手术的健康犬。
在每只犬麻醉前、麻醉期间和麻醉后放置CGMS并用于获取计算得出的血糖测量值。定期将CGMS测量值与用便携式化学分析仪（PCA）获得的外周静脉血葡萄糖浓度的同步测量值进行比较。
在大部分麻醉期间，CGMS计算得出的血糖测量值与PCA血糖测量值存在显著差异。在麻醉期间获得的126对（42.9%）配对测量值中，有54对CGMS值与PCA值相差>20%。麻醉期间，CGMS测量值中有25次（19.8%）出现明显低血糖。相比之下，同期PCA仅检测到1次低血糖事件。
不建议使用CGMS常规监测间质葡萄糖浓度作为麻醉期间血糖浓度的指标。有必要进行进一步研究以阐明麻醉期间CGMS结果与PCA数据之间差异的原因。
