Pepper T, Shekar K, Singh M, Brennan P A
Queen Alexandra Hospital, Portsmouth, United Kingdom.
Br J Oral Maxillofac Surg. 2010 Apr;48(3):208-10. doi: 10.1016/j.bjoms.2009.10.030. Epub 2009 Dec 31.
The authors present an unusual case of invasive squamous cell carcinoma (SCC) developing in a pre-existing plasmacytosis of the lip. The roles of chronic inflammation, immunosuppression, and smoking in the pathogenesis of this tumour are briefly discussed. The authors highlight a significant side effect of the use of immunosuppressive drugs in benign conditions.