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声门上黏膜浆细胞增多症:一例报告及文献综述

Supraglottic mucous membrane plasmacytosis: a case report and literature review.

作者信息

Gillanders Sarah L, Crotty Thomas J, O'Neill James P

机构信息

Department of Otolaryngology-Head and Neck Surgery, Beaumont Hospital, Dublin, Ireland.

Royal College of Surgeons Ireland, Dublin, Ireland.

出版信息

Ann Med Surg (Lond). 2025 Jan 9;87(1):335-338. doi: 10.1097/MS9.0000000000002766. eCollection 2025 Jan.

DOI:10.1097/MS9.0000000000002766
PMID:40109593
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11918545/
Abstract

INTRODUCTION

Mucous membrane plasmacytosis is a rare, inflammatory disorder characterized by polyclonal plasma cells infiltrating the mucosal tissue of the oral cavity, oropharynx, laryngopharynx, or genitalia.

CASE PRESENTATION

We present a case of supraglottic plasmacytosis which presented a management challenge due to a complicated past medical history preventing oral steroid administration.

DISCUSSION

A literature review is conducted to determine alternate treatment options in for this challenging case and others. A discussion of diagnosis, treatment and aftercare follows the case report and literature review.

CONCLUSION

This case report illustrates the rare condition of laryngeal mucous membrane plasmacytosis. Application of steroids to the specific site of pathology appears to be a promising management course.

摘要

引言

黏膜浆细胞增多症是一种罕见的炎症性疾病,其特征是多克隆浆细胞浸润口腔、口咽、下咽或生殖器的黏膜组织。

病例介绍

我们报告一例声门上浆细胞增多症病例,因其复杂的既往病史导致无法口服类固醇,给治疗带来了挑战。

讨论

进行文献综述以确定针对这一具有挑战性的病例及其他病例的替代治疗方案。病例报告和文献综述之后是关于诊断、治疗和后续护理的讨论。

结论

本病例报告说明了喉黏膜浆细胞增多症这种罕见病症。在病理特定部位应用类固醇似乎是一种有前景的治疗方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/285a/11918545/24dafcb26d83/ms9-87-335-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/285a/11918545/707038911aa4/ms9-87-335-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/285a/11918545/24dafcb26d83/ms9-87-335-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/285a/11918545/707038911aa4/ms9-87-335-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/285a/11918545/24dafcb26d83/ms9-87-335-g002.jpg

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Int J Surg. 2023 May 1;109(5):1136-1140. doi: 10.1097/JS9.0000000000000373.
2
Pitfalls and Challenges in Oral Plasma Cell Mucositis: A Systematic Review.口腔浆细胞性黏膜炎的陷阱与挑战:一项系统评价
J Clin Med. 2022 Nov 4;11(21):6550. doi: 10.3390/jcm11216550.
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Upper and Lower Respiratory Mucous Membrane Plasmacytosis with a Cobblestone Appearance: a Case Report.上、下呼吸道黏膜浆细胞增多症伴鹅卵石样外观:1例报告
Ear Nose Throat J. 2025 Mar;104(1_suppl):271S-274S. doi: 10.1177/01455613221134412. Epub 2022 Nov 10.
4
Laryngeal Plasmacytosis Responsive to Inhaled Budesonide.喉浆细胞增多症对布地奈德吸入剂的反应。
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6
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Two cases of chronic oral ulcers effectively treated with systemic corticosteroid therapy: Circumorificial plasmacytosis and traumatic ulcerative granuloma with stromal eosinophilia.两例慢性口腔溃疡经全身皮质类固醇治疗有效:环状浆细胞增多症和创伤性溃疡性嗜酸性粒细胞肉芽肿。
J Dermatol. 2019 Jan;46(1):48-51. doi: 10.1111/1346-8138.14690. Epub 2018 Oct 31.
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