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一名青年男性舌部浆细胞性粘膜炎的罕见病例。

An Uncommon Case of Plasma Cell Mucositis of the Tongue in a Young Man.

作者信息

Antonelli Alessandro, Averta Fiorella, Diodati Federica, Muraca Danila, Brancaccio Ylenia, Mignogna Chiara, Giudice Amerigo

机构信息

School of Dentistry, Department of Health Sciences, "Magna Graecia" University of Catanzaro, Italy.

Interdepartmental Service Center, "Magna Graecia" University of Catanzaro, Italy.

出版信息

Case Rep Dent. 2020 Feb 18;2020:3429632. doi: 10.1155/2020/3429632. eCollection 2020.

DOI:10.1155/2020/3429632
PMID:32148974
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7049820/
Abstract

Plasma cell mucositis (PCM) is an unusual plasma cell proliferative disorder of the upper aerodigestive tract. It is a rare disease, and its etiology is not yet known with variable clinical features. Symptoms include dysphagia, oral pain, and swelling. We described a case of PCM involving the tongue of a 14-year-old man. In the first place, several diagnostic hypotheses were proposed, most of them discarded for incompatibility with blood and laboratory tests. This disease rarely manifests itself on the tongue, especially in young patients with no comorbidities. The management of PCM is mainly aimed at reducing the symptoms, and in our report, the treatment involved the use of systemic prednisone with an improvement of the quality of life. At 1-year follow-up, there was no recurrence of the disease. Many therapeutic treatments are able to stabilize but not able to induce a complete remission. PCM is considered an uncommon benign disorder with a favorable prognosis and should be considered in the differential diagnosis with other inflammatory or neoplastic conditions.

摘要

浆细胞性黏膜炎（PCM）是上消化道一种罕见的浆细胞增殖性疾病。它是一种罕见病，病因尚不明确，临床特征多样。症状包括吞咽困难、口腔疼痛和肿胀。我们描述了一例累及一名14岁男性舌头的PCM病例。首先，提出了几种诊断假设，其中大多数因与血液和实验室检查结果不符而被排除。这种疾病很少在舌头上表现，尤其是在没有合并症的年轻患者中。PCM的治疗主要旨在减轻症状，在我们的报告中，治疗包括使用全身性泼尼松，患者生活质量得到改善。在1年的随访中，疾病未复发。许多治疗方法能够稳定病情，但无法诱导完全缓解。PCM被认为是一种预后良好的罕见良性疾病，在与其他炎症性或肿瘤性疾病进行鉴别诊断时应予以考虑。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3353/7049820/aaca37c987cf/CRID2020-3429632.013.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3353/7049820/c42c88a0c7ac/CRID2020-3429632.005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3353/7049820/8d90516cbd83/CRID2020-3429632.006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3353/7049820/02c323f41283/CRID2020-3429632.007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3353/7049820/2ae16cf94598/CRID2020-3429632.008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3353/7049820/9d4d6e535fa2/CRID2020-3429632.009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3353/7049820/b80ec27feddb/CRID2020-3429632.010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3353/7049820/f99875f9df45/CRID2020-3429632.011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3353/7049820/677cefe7f932/CRID2020-3429632.012.jpg
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